Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C

Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts Publisher

Mirfattahi M¹ ; Yazzaf R¹ ; Mahdavi M²

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1. School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Tetrahedron Letters Published:2024

Abstract

A novel cyclization of Ugi adducts through a base-mediated system has been reported. The process entails an oxygen nucleophilic attack on the alkyl halide moiety, subsequently leading to an intramolecular cyclization. These consecutive reactions are straightforward to execute, occur under mild conditions, and do not require a catalyst. This catalyst-free attribute enhances the method's utility and eco-friendliness, rendering it an appealing approach for producing this significant category of heterocyclic compounds. © 2024 Elsevier Ltd

Style	Citing Format
MLA	Mirfattahi M, Yazzaf R, Mahdavi M. "Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts." Tetrahedron Letters, vol. 141, no. , 2024, pp. -.
APA	Mirfattahi M, Yazzaf R, Mahdavi M (2024). Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts. Tetrahedron Letters, 141(), -.
Chicago	Mirfattahi M, Yazzaf R, Mahdavi M. "Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts." Tetrahedron Letters 141, no. (2024): -.
Harvard	Mirfattahi M, Yazzaf R, Mahdavi M (2024) 'Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts', Tetrahedron Letters, 141(), pp. -.
Vancouver	Mirfattahi M, Yazzaf R, Mahdavi M. Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts. Tetrahedron Letters. 2024;141():-.
BibTex	@article{ author = {Mirfattahi M and Yazzaf R and Mahdavi M}, title = {Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts}, journal = {Tetrahedron Letters}, volume = {141}, number = {}, pages = {-}, year = {2024} }
RIS	TY - JOUR AU - Mirfattahi M AU - Yazzaf R AU - Mahdavi M TI - Construction of [1,4]Oxazepin-2-Ones Via Catalyst-Free Intramolecular C–O Bond Formation From Ugi Adducts JO - Tetrahedron Letters VL - 141 IS - SP - EP - PY - 2024 ER -

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