Nail Changes in Early Mycosis Fungoides

Nail Changes in Early Mycosis Fungoides Publisher

Ehsani AH¹ ; Nasimi M¹ ; Azizpour A¹ ; Noormohammadpoor P¹ ; Kamyab K² ; Seirafi H¹ ; Noori M³

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1. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Vahdate Eslami Street, Tehran, 1199663911, Iran
2. Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
3. Tehran University of Medical Sciences, Tehran, Iran

Source: Skin Appendage Disorders Published:2018

Abstract

Background: Mycosis fungoides (MF) has a wide range of clinical presentations and it has been reported rarely to involve the nail apparatus. Objective: We intended to evaluate the frequency and characteristics of nail changes in patients with biopsy-proven MF. Methods: A retrospective analysis of 60 patients with MF who were evaluated at our cancer center from 2013 to 2014 was performed to identify patients with nail changes. Histological examinations of the skin around the nail apparatus were obtained from 10 patients with periungual skin erythema and scaling. Results: In 45 patients out of 60 cases, the skin around the nail apparatus was normal, and only in 5 patients of these 45 cases, nail changes were detected. These changes included leukonychia, longitudinal ridging, nail thickening, and opacity. In the remaining 15 patients, erythema and scaling was observed in periungual skin, and 13 of them demonstrated nail changes including longitudinal ridging, nail thickening, fragility of the nail plate, subungual hyperkeratosis, pigmented nail band, Beau's lines, onychomadesis, koilonychia, nail thinning, distal notching, subungual debris, leukonychia, and pitting. In biopsies of periungual skin, none of 10 cases revealed histological findings consistent with MF. Conclusions: Evidence of nail changes was observed in 18 cases (30%). The most common nail changes detected in MF patients included longitudinal ridging, nail thickening, nail fragility, and leukonychia. © 2017 S. Karger AG, Basel.

Style	Citing Format
MLA	Ehsani AH, et al.. "Nail Changes in Early Mycosis Fungoides." Skin Appendage Disorders, vol. 4, no. 1, 2018, pp. 55-59.
APA	Ehsani AH, Nasimi M, Azizpour A, Noormohammadpoor P, Kamyab K, Seirafi H, Noori M (2018). Nail Changes in Early Mycosis Fungoides. Skin Appendage Disorders, 4(1), 55-59.
Chicago	Ehsani AH, Nasimi M, Azizpour A, Noormohammadpoor P, Kamyab K, Seirafi H, Noori M. "Nail Changes in Early Mycosis Fungoides." Skin Appendage Disorders 4, no. 1 (2018): 55-59.
Harvard	Ehsani AH et al. (2018) 'Nail Changes in Early Mycosis Fungoides', Skin Appendage Disorders, 4(1), pp. 55-59.
Vancouver	Ehsani AH, Nasimi M, Azizpour A, Noormohammadpoor P, Kamyab K, Seirafi H, et al.. Nail Changes in Early Mycosis Fungoides. Skin Appendage Disorders. 2018;4(1):55-59.
BibTex	@article{ author = {Ehsani AH and Nasimi M and Azizpour A and Noormohammadpoor P and Kamyab K and Seirafi H and Noori M}, title = {Nail Changes in Early Mycosis Fungoides}, journal = {Skin Appendage Disorders}, volume = {4}, number = {1}, pages = {55-59}, year = {2018} }
RIS	TY - JOUR AU - Ehsani AH AU - Nasimi M AU - Azizpour A AU - Noormohammadpoor P AU - Kamyab K AU - Seirafi H AU - Noori M TI - Nail Changes in Early Mycosis Fungoides JO - Skin Appendage Disorders VL - 4 IS - 1 SP - 55 EP - 59 PY - 2018 ER -

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