Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Effect of Intracanal Cryotherapy on Post-Operative Pain in Single-Visit Endodontic Retreatment: A Randomized Clinical Trial Publisher Pubmed



Ghabraei S1 ; Afkhami F2 ; Kiafar MM1 ; Kharazifard MJ3 ; Peters OA2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Dentistry, The University of Queensland, Brisbane, Australia
  3. 3. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: BMC Oral Health Published:2024


Abstract

Background: This randomized clinical trial aimed to evaluate the effect of intracanal cryotherapy with 2–4 °C normal saline irrigation on post-operative pain after single-visit non-surgical root canal retreatment. Methods: Forty-six single-rooted, single-canal teeth requiring non-surgical root canal retreatment were randomly assigned to two groups (n = 23): a cryotherapy group and a control group. All the treatments were completed during a single visit. A combination of nickel-titanium and stainless-steel files was used for the removal of gutta-percha and root canal preparation, and irrigation was performed using 5.25% NaOCl and 17% EDTA. The cryotherapy group had a final irrigation temperature of 2–4 °C for 5 min before root canal obturation, whereas the control group received irrigation at room temperature. Post-operative pain levels were assessed via the Numerical Rating Scale at 6, 18, 24, 48, 72, and 168 h (up to 7 days). The number of analgesics consumed at the same intervals was also recorded. Statistical analysis was performed using the Chi-Square test, Mann-Whitney test, and Independent Samples test, with the significance level set at 0.05. Results: There was a statistically significant difference in post-operative pain between the cryotherapy group and the control group at 6 h after treatment (P < 0.05). However, post-operative pain levels were not significantly different at 18, 24, 48, 72, or 168 h after treatment (P > 0.05). Additionally, there was no statistically significant difference between the groups in terms of analgesic intake (P > 0.05). Conclusion: Intracanal cryotherapy can effectively reduce short-term post-operative pain, but it has no effect on long-term pain or the need for analgesics. © The Author(s) 2024.