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Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives Publisher



Mahdavi M1 ; Kianfard H2 ; Saeedi M3, 4 ; Ranjbar PR2 ; Shafiee A5
Authors

Source: Synlett Published:2016


Abstract

A simple and direct procedure was developed for the synthesis of a novel series of polyfunctionalized pyrimidines. They were prepared via reaction of N-(substituted carbamothioyl)benzimidamides (prepared from the reaction of benzimidamide hydrochloride and isothiocyanates) and malononitrile in the presence of CuBr/Et3N in DMF at 80 °C. © Georg Thieme Verlag Stuttgart, New York.
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