Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity

Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity Publisher

Manavi MA¹ ; Fathian Nasab MH¹ ; Dashti F¹ ; Moghimi S² ; Saniee P³ ; Pouramiri B⁴ ; Foroumadi A^{1, 2} ; Piralihamedani M¹

Show Affiliations

1. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran
3. Department of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran
4. Research Committee, Jiroft University of Medical Sciences, Jiroft, 76177, Iran

Source: Research on Chemical Intermediates Published:2022

Abstract

Nearly half of the world's population have been infected with Helicobacter pylori (H. pylori) which is known as the main cause of chronic gastritis, duodenal ulcer illness as well as stomach carcinoma. In this work, an efficient, one-pot synthesis of amidoalkyl naphthol derivatives and their in vitro anti-Helicobacter pylori activity are reported. The reaction proceeds via multi-component condensation of 2-naphthol, (hetero) aromatic aldehydes and urea/thiourea/acetamide/2-aminothiazole/4-nitrothiazol-2-amine/2-aminopyridine under solvent-free condition. This protocol includes some salient features, such as using triethanolammonium acetate ([OHCH2CH2)3NH][OAc]) ionic liquid as a green, clean and reusable catalyst, high yields, no column chromatography, and low cost. By comparing the inhibition zone of the target compounds, 6e and 6j could be considered as the best anti-helicobacter agent. © 2022, The Author(s), under exclusive licence to Springer Nature B.V.

Style	Citing Format
MLA	Manavi MA, et al.. "Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity." Research on Chemical Intermediates, vol. 48, no. 10, 2022, pp. 4049-4062.
APA	Manavi MA, Fathian Nasab MH, Dashti F, Moghimi S, Saniee P, Pouramiri B, Foroumadi A, Piralihamedani M (2022). Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity. Research on Chemical Intermediates, 48(10), 4049-4062.
Chicago	Manavi MA, Fathian Nasab MH, Dashti F, Moghimi S, Saniee P, Pouramiri B, Foroumadi A, Piralihamedani M. "Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity." Research on Chemical Intermediates 48, no. 10 (2022): 4049-4062.
Harvard	Manavi MA et al. (2022) 'Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity', Research on Chemical Intermediates, 48(10), pp. 4049-4062.
Vancouver	Manavi MA, Fathian Nasab MH, Dashti F, Moghimi S, Saniee P, Pouramiri B, et al.. Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity. Research on Chemical Intermediates. 2022;48(10):4049-4062.
BibTex	@article{ author = {Manavi MA and Fathian Nasab MH and Dashti F and Moghimi S and Saniee P and Pouramiri B and Foroumadi A and Piralihamedani M}, title = {Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity}, journal = {Research on Chemical Intermediates}, volume = {48}, number = {10}, pages = {4049-4062}, year = {2022} }
RIS	TY - JOUR AU - Manavi MA AU - Fathian Nasab MH AU - Dashti F AU - Moghimi S AU - Saniee P AU - Pouramiri B AU - Foroumadi A AU - Piralihamedani M TI - Green and One-Pot Synthesis of Novel Amidoalkyl Naphthols Using Triethanolammonium Acetate [(Ohch2ch2)3Nh][Oac]) Ionic Liquid and Their Anti-H.Pylori Activity JO - Research on Chemical Intermediates VL - 48 IS - 10 SP - 4049 EP - 4062 PY - 2022 ER -

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