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Comparison of Clinicodemographic Characteristics and Pattern of Vascular Involvement in 126 Patients With Takayasu Arteritis: A Report From Iran and Turkey Publisher Pubmed



Tamartash Z1 ; Javinani A1 ; Pehlivan Y2 ; Coskun BN2 ; Yekta RA3 ; Dalkilic E2 ; Yagiz B2 ; Khavandgar N1 ; Pournazari M4 ; Hajiabbasi A5 ; Sakar O6 ; Zayeni H5 ; Masoleh IS5 ; Shakibi MR7 Show All Authors
Authors
  1. Tamartash Z1
  2. Javinani A1
  3. Pehlivan Y2
  4. Coskun BN2
  5. Yekta RA3
  6. Dalkilic E2
  7. Yagiz B2
  8. Khavandgar N1
  9. Pournazari M4
  10. Hajiabbasi A5
  11. Sakar O6
  12. Zayeni H5
  13. Masoleh IS5
  14. Shakibi MR7
  15. Yazdi F8
  16. Mahmoudi M1
  17. Masoumi M9
  18. Mohammadzadegan AM1
  19. Sima F1
  20. Salehi S1
  21. Faezi ST1
  22. Jamshidi AR1
  23. Kavosi H1
Show Affiliations
Authors Affiliations
  1. 1. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Rheumatology, Uludag University, Bursa, Turkey
  3. 3. Anesthesiology Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  5. 5. Department of Rheumatology, Guilan Rheumatology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  6. 6. Department of Internal Medicine, Uludag University, Bursa, Turkey
  7. 7. Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
  8. 8. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
  9. 9. Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran

Source: Reumatismo Published:2022


Abstract

Takayasu arteritis (TA) is an extremely uncommon vasculitis that primarily affects the aorta and its branches. Due to the genetic and ethnicity effect, a diverse array of TA clinical manifestations has been reported world-wide. The purpose of the present study was to compare the clinicodemographic characteristics and pattern of vascular involvement of Iranian and Turkish TA patients. This study was a retrospective, cross-sectional investigation of 126 TA patients in Iran and Turkey. All of the variables analyzed were extracted from historical medical records. In 126 TA patients, the ratio of females to males was 8.6:1, and the average age at onset of disease was 30.5±11.1 years. Fatigue (49.2%) and a weak or absent pulse (79.4%) were the most prevalent symptoms and signs, respectively. The most prevalent angiographic classifications were types V and I in Iranian patients (41.09%) and type I in the Turkish population (47.7%) The left subclavian artery was the vessel most frequently affected by TA (66.6%). Our findings indicated that there were no significant differences between the two countries in terms of clinic-odemographic characteristics or vascular involvement. Some clinical manifestations, such as claudication, were more prevalent in the Turkish population due to a higher incidence of occlusive lesions in the right subclavian artery. © 2022, Page Press Publications. All rights reserved.