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Literature Review and Suggested Protocol for Prevention and Treatment of Corneal Graft Rejection Publisher Pubmed



Azevedo Magalhaes O1 ; Shalaby Bardan A2, 3 ; Zareighanavati M4 ; Liu C2, 5
Authors
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Authors Affiliations
  1. 1. Porto Alegre Eye Bank Hospital, Porto Alegre, Brazil
  2. 2. Sussex Eye Hospital, Brighton, United Kingdom
  3. 3. Faculty of Medicine, Alexandria University, Alexandria, Egypt
  4. 4. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Tongdean Eye Clinic, Hove, United Kingdom

Source: Eye (Basingstoke) Published:2020


Abstract

Effective prophylaxis and treatment of corneal graft rejection are essential to improve outcomes in corneal transplantation. To date, there has been no standardized protocol published that outlines the optimal prophylactic and therapeutic approaches and, furthermore, the published controlled trials on this subject are limited. Likewise, no study has addressed how the level of antigen exposure varies between different types of keratoplasties. The aim of this paper is to provide a simple evidence-based protocol for the prevention and treatment of corneal graft rejection. © 2019, The Author(s), under exclusive licence to The Royal College of Ophthalmologists.