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Nithiazine Publisher



Manavi MA1 ; Nasab MHF1 ; Baeeri M2, 3
Authors
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Authors Affiliations
  1. 1. Faculty of Pharmacy, Pharmaceutical Sciences Research Center (PSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Toxicology and Diseases Group (TDG), Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran, Iran
  3. 3. Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023


Abstract

A recent family of pesticides called neonicotinoids targets postsynaptic nicotinic acetylcholine esterase receptors. The first neonicotinoid was nithiazine, also known as 2-nitromethylene tetrahydro-1,3-thiazine, which Shell created in 1978. It is somewhat poisonous to animals and irritating to the skin and eyes. In mammals and insects, nithiazine acts as an agonist at the nicotinic acetylcholine receptor. There are two possible exposure pathways: cutaneous contact and ingestion. Nithiazine field usage has been constrained by its poor photostability. © 2024 Elsevier Inc. All rights reserved.
Related Docs
1. Neonicotinoids, Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)
Experts (# of related papers)
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Maryam Baeeri (1)