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Evaluation of Pharmacist-Based Interventions to Optimise Utilisation of Parenteral Paracetamol in a Teaching Hospital in Iran Publisher



Laali E1 ; Ghorbani A2 ; Najafi S2 ; Sarayani A3 ; Ghafari S1 ; Makarem J4 ; Khorasani G5 ; Gholami K3 ; Jahangardrafsanjani Z1, 2
Authors
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Authors Affiliations
  1. 1. Department of Pharmacotherapy, College of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Pharmaceutical Care Department, College of Pharmacy, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Anesthesiology, Faculty of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Plastic and Reconstructive Surgery Division, Faculty of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Pharmacy Practice and Research Published:2020


Abstract

This study clarified the effect of pharmacist-led interventions to decrease the cost and inappropriate prescribing of parenteral paracetamol (PP). The prescribing pattern of PP was assessed at baseline and after pharmacist-led interventions (educational and protocol interventions) in a teaching hospital in Tehran, Iran. Comparison of appropriate dosage form between baseline and postintervention assessments indicated a significant difference (55.6% vs 77.6%, respectively; p < 0.001). Educational intervention significantly improved the appropriate duration of PP administration from baseline to postintervention (29% vs 41.7%, respectively; p = 0.006), but had no significant effect on the appropriateness of dosing. The mean monthly number of vials used decreased considerably following the educational and protocol interventions (25% (p = 0.002) and 59% (p < 0.001) reductions, respectively). Thus, incorporating educational and protocol interventions could promote the appropriate prescription and rational use of PP and aid in reducing its financial burden. © 2020 The Society of Hospital Pharmacists of Australia