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Physiologic Function of Mediastinum Space Publisher



Azimi G1 ; Bozorgmehr R2 ; Sattari P3 ; Azimi A4 ; Azimi H4 ; Marzbanrad S5
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, School of Medicine, Shahed University, Tehran, Iran
  2. 2. School of Medicine, Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. General Practitioner, Institute of Health Education and Research, Chamran Hospital, Tehran, Iran
  4. 4. Student of Research Committee, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  5. 5. Department of Surgery, Imam-Reza Hospital, Aja University of Tehran Medical Sciences, Tehran, Iran

Source: Annals of Medicine and Surgery Published:2022


Abstract

The mediastinum forms the central part of the thoracic cavity that is surrounded by pleural space on the two sides, thoracic vertebrae at the posterior, thoracic inlet on the top, and diaphragm at the bottom. It encompasses cardiopulmonary organs and organ systems. Pathological dysfunction or deformity in any part of the mediastinum can have adverse cardiovascular and respqiratory effects. Pectus excavatum and pectus carinatum are the most common congenital chest deformities that are characterized by sternal depression and protuberance of the sternum, respectively. Together, these account for 90% of chest wall deformities. Patients are known to be represented with respiratory distress and cardiovascular dysfunction. The aim of the review article is to present the anatomical and physiological role of the mediastinum in association with important parts of the thoracic cavity and pathological dysfunction of the mediastinum (cardiopulmonary system) due to pectus excavatum and pectus carinatum. © 2022 The Authors