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Aspergilloma As a Skull Base Tumor: A Case Report Publisher



Nasirmohtaram S1 ; Tabari A2 ; Zeinalizadeh M3 ; Salehi M4 ; Hosseini SMS2
Authors
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Authors Affiliations
  1. 1. Otorhinolaryngology Research Center, Guilan University of Medical Sciences, Rasht, Iran
  2. 2. Otorhinolaryngology Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Neurosurgery and Skull Base Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of infectious diseases and Tropical Medicine, Antibiotic Stewardship & Antimicrobial Resistance Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Caspian Journal of Neurological Sciences Published:2025


Abstract

Background: Aspergillosis is a fungus-related health problem that may include allergic reactions like allergic bronchopulmonary aspergillosis, which presents as upper and lower airway disease or chronic and invasive forms of fungal infection. Case Presentation: Here, we report a young woman with a history of poorly controlled asthma. She was primarily diagnosed with a skull base tumor due to the left eye proptosis and soft tissue mass involving the orbit and skull base, with intracranial extension. The diagnosis of aspergillosis was confirmed after tissue sampling, and the patient was successfully managed with an oral anti-fungal agent. Conclusion: Aspergillosis could be a differential diagnosis in the patients presenting with skull base tumor and a positive history of allergic asthma. © 2025 The Author(s);