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The Minimal Clinically Important Difference of Two Multifaceted Fatigue Evaluation Questionnaires in Chronic Stroke Publisher Pubmed



Fallah S1 ; Parnain Z2 ; Taghaviazarsharabiani P3 ; Cheraghifard M4 ; Vasaghigharamaleki B5 ; Roohiazizi M5 ; Hashemi M6 ; Yousefi M2 ; Joghataei MT7, 8 ; Taghizadeh G9
Authors
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Authors Affiliations
  1. 1. Department of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran
  2. 2. Department of Occupational Therapy, Iran University of Medical Sciences (IUMS), Tehran, Iran
  3. 3. Shafa Yahyaeian Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran
  4. 4. Rehabilitation Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran
  5. 5. Rehabilitation Research Center, Department of Basic Sciences in Rehabilitation, School of Rehabilitation Sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran
  6. 6. Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  7. 7. Department of Anatomy, School of Medicine Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran
  8. 8. Department of Innovation in Medical Education, Faculty of Medicine, Ottawa University, Ottawa, Canada
  9. 9. Geriatric Mental Health Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Topics in Stroke Rehabilitation Published:2025


Abstract

Purpose: This research sought to ascertain the Minimal Clinically Important Difference (MCID) and Robust Clinically Important Difference (RCID) of the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF) and Chalder Fatigue Questionnaire-11 (CFQ-11) as two important concepts for the clinical interpretation of the results in chronic post-stroke population. Methods: A total of 128 subjects with chronic post-stroke completed the MFSI-SF and CFQ-11 before and after six weeks of intervention. The MCIDs were derived using both anchor- and distribution-based methods; however, only anchor-based methods were used to estimate RCIDs. Results: Anchor-based MCIDs for MFSI-SF and CFQ-11 were in the range of −5 to −6.28 and −2 to −4.56, respectively. Distribution-based MCIDs in MFSI-SF and CFQ-11 were calculated in the range of −4.17 to −24.05 and −1.72 to −7.68, respectively. RCID ranges of −10 to −15 were obtained for the MFSI-SF and −6 to −7.33 for the CFQ-11. Conclusion: These findings may have implications for clinical experts in the clinical interpretation of fatigue changes observed in MFSI-SF and CFQ-11 in individuals with chronic stroke. © 2024 Taylor & Francis Group, LLC.
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