Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report

Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report Publisher Pubmed

Rahmani H¹ ; Radmehr M¹ ; Hadjibabaie M¹ ; Solduzian M¹

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1. Clinical Pharmacy Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Oncology Pharmacy Practice Published:2020

Abstract

Cytarabine is a pyrimidine analogue that is used for the treatment of acute myeloid leukemia at different doses. Standard doses of cytarabine are used for induction therapy, while high doses are used for post-remission (consolidation) and relapsed/refractory treatment. One of the major side effects of its high doses is acute cerebellar toxicity occurring in 10 to 25% of patients. We report a case that developed this side effect after receiving two doses of high-dose cytarabine. The patient’s symptoms improved after withholding the drug. Thereafter, the patient tolerated treatment continuation with lower doses. © The Author(s) 2020.

Style	Citing Format
MLA	Rahmani H, et al.. "Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report." Journal of Oncology Pharmacy Practice, vol. 26, no. 6, 2020, pp. 1492-1494.
APA	Rahmani H, Radmehr M, Hadjibabaie M, Solduzian M (2020). Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report. Journal of Oncology Pharmacy Practice, 26(6), 1492-1494.
Chicago	Rahmani H, Radmehr M, Hadjibabaie M, Solduzian M. "Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report." Journal of Oncology Pharmacy Practice 26, no. 6 (2020): 1492-1494.
Harvard	Rahmani H et al. (2020) 'Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report', Journal of Oncology Pharmacy Practice, 26(6), pp. 1492-1494.
Vancouver	Rahmani H, Radmehr M, Hadjibabaie M, Solduzian M. Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report. Journal of Oncology Pharmacy Practice. 2020;26(6):1492-1494.
BibTex	@article{ author = {Rahmani H and Radmehr M and Hadjibabaie M and Solduzian M}, title = {Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report}, journal = {Journal of Oncology Pharmacy Practice}, volume = {26}, number = {6}, pages = {1492-1494}, year = {2020} }
RIS	TY - JOUR AU - Rahmani H AU - Radmehr M AU - Hadjibabaie M AU - Solduzian M TI - Acute Cerebellar Toxicity Induced by High Dose of Cytarabine (Hidac): A Case Report JO - Journal of Oncology Pharmacy Practice VL - 26 IS - 6 SP - 1492 EP - 1494 PY - 2020 ER -

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