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A Systematic Review on Covid-19 Vaccination and Cosmetic Filler Reactions: A Focus on Case Studies and Original Articles Publisher Pubmed



Kalantari Y1, 2 ; Aryanian Z2, 3 ; Mirahmadi SMS4 ; Alilou S5 ; Hatami P2 ; Goodarzi A6, 7
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Autoimmune Bullous Diseases Research Cente, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Dermatology, Babol University of Medical Sciences, Babol, Iran
  4. 4. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  6. 6. Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Cosmetic Dermatology Published:2022


Abstract

Background: Tissue fillers are among the most popular cosmetic procedures performed and notably, cases of filler reactions after COVID-19 vaccination have been reported. Objective: The objective was to determine the characteristics of patients with filler reaction after COVID-19 vaccination and address several considerations that have to be taken into practice. Methods: A PRISMA compliant systematic search was conducted in Scopus, Web of Science, and PubMed/MEDLINE databases for articles published from inception up to October 21, 2021. Results: Out of 106 initially retrieved articles, four of them were included in our study, and a total number of 13 cases were analyzed. In this study, we found that all of the patients who developed delayed-type reaction (DTR) following COVID-19 vaccination were middle-aged women without any known history of allergy to foods or drugs. All patients had a history of hyaluronic acid (HA) filler injection in their head and neck and demonstrated symptoms particularly swelling, from <1 day up to 10 days after the first or second doses of vaccines. Lisinopril, hyaluronidase, and corticosteroids seemed to have good results in management. Conclusion: Although rare, DTR to fillers after COVID-19 vaccination can happen. Physicians should be aware of the pathogenesis and management of this phenomenon. © 2022 Wiley Periodicals LLC.
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