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Post-Icu Psychological Morbidity in Very Long Icu Stay Patients With Ards and Delirium Publisher Pubmed



Bashar FR1 ; Vahedianazimi A2 ; Hajiesmaeili M3 ; Salesi M4 ; Farzanegan B5 ; Shojaei S3 ; Goharani R3 ; Madani SJ6 ; Moghaddam KG7 ; Hatamian S8 ; Moghaddam HJ9 ; Mosavinasab SMM2 ; Elamin EM10, 11 ; Miller AC12, 13
Authors
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Authors Affiliations
  1. 1. Anesthesia and Critical Care Department, Hamedan University of Medical Sciences, Hamedan, Iran
  2. 2. Trauma Research Center, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran
  3. 3. Anesthesiology Research Center, Anesthesia and Critical Care Department, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Research Center for Prevention of Oral and Dental Disease, Baqiyatallah University of Medical Sciences, Tehran, Iran
  5. 5. Tracheal Diseases Research Center, Anesthesia and Critical Care Department, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. Trauma Research Center, Medicine Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran
  7. 7. Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Anesthesia and Critical Care Department, Alborz University of Medical Sciences, Karaj, Iran
  9. 9. Anesthesiology Research Center, Anesthesia Care Department, Modares Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Department of Medicine, Division of Pulmonary, Critical Care Medicine and Sleep, University of South Florida, Tampa, FL, United States
  11. 11. Department of Medicine, Division of Pulmonary, Critical Care Medicine and Sleep, James A. Haley Veteran Hospital, Tampa, FL, United States
  12. 12. Department of Emergency Medicine, J.W. Ruby Memorial Hospital, West Virginia University, Morgantown, WV, United States
  13. 13. Department of Emergency Medicine, Vident Medical Center, East Carolina University, Greenville, NC, United States

Source: Journal of Critical Care Published:2018


Abstract

Purpose We investigated the impact of delirium on illness severity, psychological state, and memory in acute respiratory distress syndrome patients with very long ICU stay. Materials and methods Prospective cohort study in the medical-surgical ICUs of 2 teaching hospitals. Very long ICU stay (> 75 days) and prolonged delirium (≥ 40 days) thresholds were determined by ROC analysis. Subjects were ≥ 18 years, full-code, and provided informed consent. Illness severity was assessed using Acute Physiology and Chronic Health Evaluation IV, Simplified Acute Physiology Score-3, and Sequential Organ Failure Assessment scores. Psychological impact was assessed using the Hospital Anxiety and Depression Scale, Impact of Event Scale-Revised, and the 14-question Post-Traumatic Stress Syndrome (PTSS-14). Memory was assessed using the ICU Memory Tool survey. Results 181 subjects were included. Illness severity did not correlate with delirium duration. On logistic regression, only PTSS-14 < 49 correlated with delirium (p = 0.001; 95% CI 1.011, 1.041). 49% remembered their ICU stay clearly. 47% had delusional memories, 50% reported intrusive memories, and 44% reported unexplained feelings of panic or apprehension. Conclusion Delirium was associated with memory impairment and PTSS-14 scores suggestive of PTSD, but not illness severity. © 2017