Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome

Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome Publisher

Fattahi A¹ ; Sayyahfar S² ; Lotfali E³ ; Ghasemi R⁴ ; Mortezaeian H⁵

Show Affiliations

1. Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
2. Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
3. Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5. Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

Source: Current Medical Mycology Published:2020

Abstract

Background and Purpose: Aspergillus species are implicated as the etiology of approximately 26% of endocarditis cases. Central nervous system aspergillosis is a life-threatening condition that has a mortality rate of 80%. Case report: Herein, we report a four- year- old female who was admitted to the pediatric infectious ward due to a fever of unknown origin in January 2020. She was a known case of Marfan syndrome with a family history of this syndrome in her mother. The species was identified using (PCR) and the antifungal susceptibility test was performed using four antifungal agents based on the Clinical and Laboratory Standards Institute M38 3rd edition. Fluconazole-resistant Aspergillus flavus was identified to be responsible for endocarditis and meningitis as well as fever of unknown origin. Conclusion: The clinicians should be aware and consider fungal endocarditis in blood culture-negative endocarditis even in patients with no significant risk factor when antibiotic therapy fails. © 2022, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center.

Style	Citing Format
MLA	Fattahi A, et al.. "Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome." Current Medical Mycology, vol. 6, no. 4, 2020, pp. 70-74.
APA	Fattahi A, Sayyahfar S, Lotfali E, Ghasemi R, Mortezaeian H (2020). Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome. Current Medical Mycology, 6(4), 70-74.
Chicago	Fattahi A, Sayyahfar S, Lotfali E, Ghasemi R, Mortezaeian H. "Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome." Current Medical Mycology 6, no. 4 (2020): 70-74.
Harvard	Fattahi A et al. (2020) 'Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome', Current Medical Mycology, 6(4), pp. 70-74.
Vancouver	Fattahi A, Sayyahfar S, Lotfali E, Ghasemi R, Mortezaeian H. Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome. Current Medical Mycology. 2020;6(4):70-74.
BibTex	@article{ author = {Fattahi A and Sayyahfar S and Lotfali E and Ghasemi R and Mortezaeian H}, title = {Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome}, journal = {Current Medical Mycology}, volume = {6}, number = {4}, pages = {70-74}, year = {2020} }
RIS	TY - JOUR AU - Fattahi A AU - Sayyahfar S AU - Lotfali E AU - Ghasemi R AU - Mortezaeian H TI - Aspergillus Flavus Endocarditis and Meningitis in a Child With Marfan Syndrome JO - Current Medical Mycology VL - 6 IS - 4 SP - 70 EP - 74 PY - 2020 ER -

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