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Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review Publisher



Hoveidaei A1 ; Tavakoli Y2 ; Ramezanpour MR3 ; Omourikharashtomi M4 ; Taghavi SP5, 6 ; Hoveidaei AH7 ; Conway JD7
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Authors Affiliations
  1. 1. Exceptional Talents Development Center, Tehran University of Medical Sciences, Tehran, 1936893813, Iran
  2. 2. Student Research Committee, Department of Medicine, Mazandaran University of Medical Science, Sari, 4815733971, Iran
  3. 3. School of Medicine, Tehran University of Medical Sciences, Tehran, 1936893813, Iran
  4. 4. Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, 6135715794, Iran
  5. 5. Student Research Committee, Kashan University of Medical Sciences, Kashan, 8713783976, Iran
  6. 6. School of Medicine, Kashan University of Medical Sciences, Kashan, 8713783976, Iran
  7. 7. International Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, 21215, MD, United States

Source: Microorganisms Published:2025


Abstract

Various imaging methods assist in diagnosing periprosthetic joint infection (PJI). These include radiological techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US); as well as advanced nuclear medicine techniques including bone scintigraphy (BS), anti-granulocyte antibody imaging (AGS), leukocyte scintigraphy (LS), and fluorodeoxyglucose positron emission tomography (FDG-PET and FDG-PET/CT). Each imaging technique and radiopharmaceutical has been extensively studied, with unique diagnostic accuracy, limitations, and benefits for PJI diagnosis. This review aims to detail and describe the most commonly used imaging techniques and radiopharmaceuticals for evaluating PJI, focusing particularly on knee and hip arthroplasties. © 2024 by the authors.
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