Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties

Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties Publisher

Salehi M¹ ; Naseri Nosar M² ; Amani A¹ ; Azami M¹ ; Tavakol S¹ ; Ghanbari H¹

Show Affiliations

1. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, 1417755469, Iran
2. Department of Biomaterials and Tissue Engineering, Biomedical Engineering Faculty, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2015

Abstract

The aim of this work was to prepare the scaffolds of pure poly (L-lactic acid) 3% (w/v), pure chitosan 3% (w/v), and PLLA/chitosan blend (1:5) 3% (w/v) using TIPS method and investigate their properties and application in tissue engineering. An in vitro degradation study of scaffolds showed the addition of chitosan to PLLA not only increased its degradation rate, but also slowed down its pH value reduction. Addition of chitosan to PLLA increased hydrophilicity, porosity, compressive properties, and cell viability of the scaffolds. The results indicate that among all scaffolds, the most appropriate candidate for tissue engineering is PLLA/chitosan blend. Copyright © Taylor & Francis Group, LLC.

Style	Citing Format
MLA	Salehi M, et al.. "Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 64, no. 13, 2015, pp. 675-682.
APA	Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H (2015). Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties. International Journal of Polymeric Materials and Polymeric Biomaterials, 64(13), 675-682.
Chicago	Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H. "Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties." International Journal of Polymeric Materials and Polymeric Biomaterials 64, no. 13 (2015): 675-682.
Harvard	Salehi M et al. (2015) 'Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties', International Journal of Polymeric Materials and Polymeric Biomaterials, 64(13), pp. 675-682.
Vancouver	Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H. Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties. International Journal of Polymeric Materials and Polymeric Biomaterials. 2015;64(13):675-682.
BibTex	@article{ author = {Salehi M and Naseri Nosar M and Amani A and Azami M and Tavakol S and Ghanbari H}, title = {Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {64}, number = {13}, pages = {675-682}, year = {2015} }
RIS	TY - JOUR AU - Salehi M AU - Naseri Nosar M AU - Amani A AU - Azami M AU - Tavakol S AU - Ghanbari H TI - Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties JO - International Journal of Polymeric Materials and Polymeric Biomaterials VL - 64 IS - 13 SP - 675 EP - 682 PY - 2015 ER -

Style

Citing Format

MLA

Salehi M, et al.. "Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 64, no. 13, 2015, pp. 675-682.

APA

Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H (2015). Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties. International Journal of Polymeric Materials and Polymeric Biomaterials, 64(13), 675-682.

Chicago

Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H. "Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties." International Journal of Polymeric Materials and Polymeric Biomaterials 64, no. 13 (2015): 675-682.

Harvard

Salehi M et al. (2015) 'Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties', International Journal of Polymeric Materials and Polymeric Biomaterials, 64(13), pp. 675-682.

Vancouver

Salehi M, Naseri Nosar M, Amani A, Azami M, Tavakol S, Ghanbari H. Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties. International Journal of Polymeric Materials and Polymeric Biomaterials. 2015;64(13):675-682.

BibTex

@article{ author = {Salehi M and Naseri Nosar M and Amani A and Azami M and Tavakol S and Ghanbari H}, title = {Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {64}, number = {13}, pages = {675-682}, year = {2015} }

RIS

TY - JOUR
AU - Salehi M
AU - Naseri Nosar M
AU - Amani A
AU - Azami M
AU - Tavakol S
AU - Ghanbari H
TI - Preparation of Pure Plla, Pure Chitosan, and Plla/Chitosan Blend Porous Tissue Engineering Scaffolds by Thermally Induced Phase Separation Method and Evaluation of the Corresponding Mechanical and Biological Properties
JO - International Journal of Polymeric Materials and Polymeric Biomaterials
VL - 64
IS - 13
SP - 675
EP - 682
PY - 2015
ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract