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A Simple Approach for Diagnosis of Chronic Tuberculous Osteomyelitis: A Case Report Publisher



Salehi M1 ; Dehghan Manshadi SA1 ; Yassin Z2 ; Hassannejad M1
Authors
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Authors Affiliations
  1. 1. Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Infectious Diseases, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran

Source: Archives of Clinical Infectious Diseases Published:2017


Abstract

Introduction: Osteomyelitis is a secondary complication in 1% to 3% of patients with pulmonary tuberculosis (TB). Definite diagnosis of TB-associated osteomyelitis is challenging for clinicians, as biopsies of deep osteoarticular tissues are necessary. Case Presentation: We present the case of a 50-year-old man, admitted to Imam Khomeini hospital, Tehran, Iran in March 2014. According to his self-report, he had a chronic ulcer on his left foot since September 2012. In physical examinations, there was a painful sinus tract orifice (2 × 2 cm) on the left medial malleolus. Magnetic resonance imaging (MRI) of the foot revealed osteomyelitis in the left ankle. Two biopsies were taken from the wound edge, and Mycobacterium tuberculosis was detected via polymerase chain reaction (PCR) assay. Conclusions: Today, in the diagnosis of TB-associated osteomyelitis, it is a common practice to obtain 3 osteoarticular tissue biopsies for microbiological evaluation, PCR analysis, and histopathological assessment. We suspect that biopsies from the edge of the sinus tract orifice may help diagnose TB osteomyelitis. © 2017, Archives of Clinical Infectious Diseases.