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A Narrative Review Study on the Effects of Obesity and Bariatric Surgery on Multiple Sclerosis Publisher



Abna Z1 ; Fazeli S2 ; Mirhashemi S3 ; Mirzaei K4 ; Emami F5, 6 ; Jamili S5, 6 ; Dehghani R7
Authors
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Authors Affiliations
  1. 1. Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Nephrologist, Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Associate Professor of General Surgery (Fellowship of Minimally Invasive Surgery), Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. General Surgeon (Fellowship of Minimally Invasive Surgery), Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. General Surgeon (Fellowship of Minimally Invasive Surgery), Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Department of Pharmacology, Bam University of Medical Sciences, Bam, Iran

Source: Annals of Indian Academy of Neurology Published:2021


Abstract

Obesity is a major public health concern and should be considered in autoimmune inflammatory disorders, such as multiple sclerosis (MS). In these patients, obesity leads to increasing comorbidities as well as reduced quality of life. Obesity causes an inflammatory state in the body, especially in adolescents; obesity has a role in the pathogenesis of MS. Hence, it is identified as a lifestyle modifiable risk factor for MS disease. Among various treatments for obesity, bariatric surgery has been widely used. Although few studies have been performed on bariatric surgery in MS patients, in this review, we present the existing data regarding the effects of obesity on the MS course and evaluate the outcomes of bariatric surgery among this population. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.
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