Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?

Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both? Publisher Pubmed

Sharifabadi AH¹ ; Haeri H¹ ; Zeinalizadeh M² ; Zargari N³ ; Razavi AE⁴ ; Shahbazi N¹ ; Tahvildari M² ; Azmoudehardalan F¹

Show Affiliations

1. Pathology and Laboratory Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, 14197-33141, Iran
2. Neurosurgery Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, 14197-33141, Iran
3. Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, 14197-33141, Iran
4. Iran National Tumor Bank, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, 14197-33141, Iran

Source: Pathology Research and Practice Published:2016

Abstract

Objective: Frozen section is the traditional method of assessing central nervous system (CNS) lesions intraoperatively. Our aim is to determine the diagnostic accuracy of frozen section and/or cytological evaluation of CNS lesions in our center. Study design: A total of 157 patients with CNS lesions underwent open surgical biopsy or excision in our center during a period of 2 years (2012-2013). All specimens were studied cytologically; of these specimens, 146 cases were also examined by frozen section. Cytology and frozen section slides were studied separately by two general pathologists who were blind to final diagnoses. The final diagnoses were based on permanent sections and IHC studies. Results: The accuracy rates of frozen section analysis and cytological evaluation were 87% and 86%, respectively. If the two methods were considered together, the accuracy rate improved to about 95%. Conclusions: Cytological evaluation is an acceptable alternative to frozen section analysis and also a great supplement to the diagnosis of CNS lesions. © 2015 Elsevier GmbH.

Related Docs

1. Diagnostic Accuracy of Frozen Section of Central Nervous System Lesions: A 10-Year Study, Iranian Journal of Child Neurology (2015)

Style	Citing Format
MLA	Sharifabadi AH, et al.. "Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?." Pathology Research and Practice, vol. 212, no. 3, 2016, pp. 179-184.
APA	Sharifabadi AH, Haeri H, Zeinalizadeh M, Zargari N, Razavi AE, Shahbazi N, Tahvildari M, Azmoudehardalan F (2016). Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?. Pathology Research and Practice, 212(3), 179-184.
Chicago	Sharifabadi AH, Haeri H, Zeinalizadeh M, Zargari N, Razavi AE, Shahbazi N, Tahvildari M, Azmoudehardalan F. "Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?." Pathology Research and Practice 212, no. 3 (2016): 179-184.
Harvard	Sharifabadi AH et al. (2016) 'Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?', Pathology Research and Practice, 212(3), pp. 179-184.
Vancouver	Sharifabadi AH, Haeri H, Zeinalizadeh M, Zargari N, Razavi AE, Shahbazi N, et al.. Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?. Pathology Research and Practice. 2016;212(3):179-184.
BibTex	@article{ author = {Sharifabadi AH and Haeri H and Zeinalizadeh M and Zargari N and Razavi AE and Shahbazi N and Tahvildari M and Azmoudehardalan F}, title = {Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both?}, journal = {Pathology Research and Practice}, volume = {212}, number = {3}, pages = {179-184}, year = {2016} }
RIS	TY - JOUR AU - Sharifabadi AH AU - Haeri H AU - Zeinalizadeh M AU - Zargari N AU - Razavi AE AU - Shahbazi N AU - Tahvildari M AU - Azmoudehardalan F TI - Intraoperative Consultation of Central Nervous System Lesions. Frozen Section, Cytology or Both? JO - Pathology Research and Practice VL - 212 IS - 3 SP - 179 EP - 184 PY - 2016 ER -

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