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A Rare Case Report of Postmenopausal Virilization: Ovarian Steroid Cell Tumor



Ebrahimpur M1 ; Mohajeritehrani MR2 ; Saffar H3 ; Sani MP1
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Medica Iranica Published:2019

Abstract

Ovarian steroid cell tumors are rare, life-threatening neoplasms that make about 0.1% of all primary ovarian tumors. They frequently present in premenopausal women with the manifestation of virilization. We report a 58-year-old postmenopausal woman that referred to our clinic with clinical manifestation of virilization. Laboratory findings showed markedly elevated serum testosterone level and ultrasound showed 2 follicles with 7 mm diameters in the left ovary. She treated by bilateral salpingo-oophorectomy and synchronous hysterectomy. Histological pathology confirmed a benign steroid cell tumor. The presentation of new-onset and rapid progressive hyperandrogenism is rare in postmenopausal women. In diagnosis, we must consider adrenal and ovarian malignancies. Stromal luteoma is a rare benign ovarian tumor, Which is treated with surgical treatment. © 2019, Medical Sciences University of Teheran. All rights reserved.