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Novel Antibacterial Biodegradable Fe-Mn-Ag Alloys Produced by Mechanical Alloying Publisher Pubmed



Sotoudehbagha P1 ; Sheibani S2 ; Khakbiz M1 ; Ebrahimibarough S3 ; Hermawan H4
Authors
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Authors Affiliations
  1. 1. Division of Biomedical Engineering, Faculty of New Sciences and Technologies, University of Tehran, Karegar Ave., P.O. Box 14395-1561, Tehran, Iran
  2. 2. School of Metallurgy and Materials Engineering, College of Engineering, University of Tehran, Tehran, Iran
  3. 3. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Mining, Metallurgical and Materials Engineering, CHU de Quebec Research Center, Laval University, Quebec City, Canada

Source: Materials Science and Engineering C Published:2018


Abstract

Various compositions and synthesis methods of biodegradable iron-based alloys have been studied aiming for the use of temporary medical implants. However, none is focused on nano-structured alloy and on adding antibacterial property to the alloy. In this study, new Fe-30Mn-(1–3)Ag alloys were synthesized by means of mechanical alloying and assessed for their microstructure, mechanical properties, corrosion rate, antibacterial activity and cytotoxicity. Results showed that the alloy with 3 wt% Ag content displayed the highest relative density, shear strength, micro hardness and corrosion rate. However, optimum cytotoxicity and the antibacterial activity were reached by the alloy with 1 wt% Ag content. The compositional and processing effects of the alloys' properties are further discussed in this work. © 2018 Elsevier B.V.
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Somayeh Ebrahimi Barough (2)