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Cytomegalovirus Colitis in a Child With Leukemia: A Case Report Publisher Pubmed



Nourbakhsh SMK1 ; Daneshjoo K1 ; Bahadoram M2 ; Ataeepour M1 ; Hassanzadeh S2
Authors
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Authors Affiliations
  1. 1. Department of Pediatric Hematology and Oncology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, 1416753955, Iran
  2. 2. Thalassemia and Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, 15794 - 61357, Iran

Source: Future Microbiology Published:2022


Abstract

A 17-month-old boy with a known case of T-cell acute lymphoblastic leukemia was admitted to the authors' hospital because of blood-streaked diarrhea a week after his last chemotherapy session. Initially, he was treated with supportive care and an empiric regimen for opportunistic causes of diarrhea; however, this was not effective. Eventually, evaluation of his stool with PCR showed positivity for cytomegalovirus. Consequently, he responded dramatically to treatment with ganciclovir. Although cytomegalovirus colitis is rare, a few case reports suggest cytomegalovirus as a possible cause of colitis in children with leukemia, which can be fatal and should be considered as a differential diagnosis. © 2022 Future Medicine Ltd.