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Managing the Dual Diagnosis Dilemma of Bipolar Disorder and Substance Abuse in Clinical Settings Publisher Pubmed



Samimi Ardestani SM1 ; Aminesmaeili M2 ; Seif P3 ; Gudarzi SS4 ; Rafiefarahzadi M5 ; Semnani Y1
Authors
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Authors Affiliations
  1. 1. Department of Psychiatry, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Associate Professor of Psychiatry, Iranian National Center for Addiction Studies (INCAS), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Postdoc Research Fellowship, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, United States
  4. 4. Eastern Health, Melbourne, Australia
  5. 5. Private Practice Psychiatrist, Tehran, Iran

Source: Journal of Dual Diagnosis Published:2024


Abstract

Objective: Drug addiction is a chronic mental disorder that significantly impacts all aspects of an individual’s life, and substance use disorder in patients with bipolar disorder. The objective of this study is to assess the frequency of substance abuse among patients with bipolar spectrum disorder. Method: This cross-sectional study evaluated the frequency of bipolar spectrum disorder in patients taking methadone through various screening measures, including Mini Mental State Examination (MMSE), DSM IV criteria, Mood Disorders Questionnaire (MDQ), Goodwin and Ghaemi’s criteria, and Akiskal classification for bipolar disorders. Results: Out of the total 197 participants in the study, 77 were identified as individuals engaging in poly-substance abuse. The investigation assessed the frequency of bipolar spectrum disorder based on various diagnostic criteria: 24% according to DSM-IV criteria, 29.9% using MDQ, 29.9% based on Ghaemi and Goodwin’s criteria, and the highest rate at 48.2% when applying Akiskal’s classification. Conclusions: This study highlights the high frequency of bipolar disorder among individuals with substance use disorder, especially those with concomitant depression. Therefore, it is crucial to pay special attention to individuals with substance use disorder with co-existing bipolar disorder. © 2024 Taylor & Francis Group, LLC.