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A Systematic Review on Human Exposure to Organophosphorus Pesticides in Iran Publisher Pubmed



Shadboorestan A1 ; Vardanjani HM2 ; Abdollahi M1 ; Goharbari MH1 ; Khanjani N3
Authors
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Authors Affiliations
  1. 1. Department of Toxicology and Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
  3. 3. Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran

Source: Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews Published:2016


Abstract

Human exposure to organophosphorus (OP) pesticides is a serious health challenge. We conducted a systematic review by searching international and national databases for published literature on any human exposure to OPs in Iran from 1990 to March 2015. Qualified papers were in two categories including studies in which biomarkers of exposure were assessed (n = 13; total no. of subjects = 759) and studies that had reported prevalence of OPs-induced poisoning (OPP) and mortality (n = 26; total no. of subjects = 5428). The mean level of activity of acetyl-cholinesterase and butyryl-cholinesterase were 68.65% and 74.2%, respectively. Overall proportion (%) of OPP was estimated (16; 95% CI, 14 to 19). © 2016 Taylor & Francis Group, LLC.
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