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Feasibility of Using Micro Silica Bead Tlds for In-Vivo Dosimetry of Ct-Based Hdr Prostate Brachytherapy: An Experimental and Simulation Study Publisher Pubmed



Siavashpour Z1 ; Kiarad R2 ; Aghamiri MR2 ; Babaloui S3 ; Seiri M3, 4 ; Jaberi R5, 6
Authors
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Authors Affiliations
  1. 1. Radiotherapy Oncology Department, Shohada-e Tajrish Educational Hospital, Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran
  3. 3. Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Science, Tehran, Iran
  4. 4. Advanced Medical Technologies & Equipment Institute, Tehran University of Medical Science, Tehran, Iran
  5. 5. Radiation Oncology Research Center, Iran Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Physics, University of Surrey, Guildford, United Kingdom

Source: Applied Radiation and Isotopes Published:2024


Abstract

Purpose: Feasibility of silica-based dosimeters for IVD of HDR prostate brachytherapy. Material and methods: Plastic dosimeter holders and a water-fillable prostate phantom were built in-house. Interstitial prostate brachytherapy and Monte Carlo simulations were performed. The treatment planning, Monte-Carlo simulation, and dosimetry results were compared. Results: The relative differences between TLD-TPS, TLD-MCNP, and TPS-MCNP were 0.2–6.9 %, 0.5–6.5 %, and 0.6–6.3 %, respectively. Conclusion: Micro-silica bead dosimeters can perform offline in situ quality assurance in HDR prostate brachytherapy. © 2024 Elsevier Ltd