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Evaluating the Impact of Covid-19 Pandemic on Organ Donation and Transplantation Activities in Iran Publisher



Latifi M1 ; Bagherpour F1 ; Jafarian A2 ; Hamidiyeh A2, 3 ; Javandoost E4 ; Mansouri Z1 ; Pourhosien M1 ; Tirgar N2 ; Amirkhani MA5, 6 ; Dehghani S1, 2
Authors
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Authors Affiliations
  1. 1. Organ Procurement Unit, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Iranian Tissue Bank & Research Center, Gene, Cell & Tissue Research institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Professor of Pediatric Hematology/Oncology and Stem Cell Transplantation, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
  5. 5. Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Stem Cell And Regenerative Medicine Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran

Source: Shiraz E Medical Journal Published:2022


Abstract

Background: Coronavirus disease 2019 (COVID-19) pandemic has had a great impact on reducing organ transplantation activities. Objectives: The aim of this study was to determine the donation and transplantation activities before and after COVID-19 outbreak in Iran. Methods: This retrospective study compared the donation and transplantation activities in two specific 9-month periods (Average period of March-Dec 2018-2019 Vs. March-Dec 2020). The questionnaire included the numbers of brain death confirmations, family consents, organ recoveries, and transplanted solid organs. The questionnaire was sent by email to the chief executive of the organ procurement unit. Results: A total of 15 organ procurement units responded to the survey. The largest reduction was seen in tissue transplantations (62.5%) during two time intervals. Brain death due to head trauma significantly decreased in two time intervals and suicide increased by 14.44% during the COVID-19 pandemic compared to 2018-2019 period. Significant reductions between the median of donation (P = 0.0187), median of potential donor (P = 0.005), median of family consent (P = 0.002), and median of eligible donor (P = 0.009) were observed during the two time periods. Conclusions: A significant reduction was observed in organ donation and transplantation during COVID-19 pandemic. Developing protocols and establishing new strategies for evaluation of organ donation to ensure the safety of organ recipients and medical staff is necessary. © 2021, Author(s).