Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis

Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis Publisher Pubmed

Karimizadeh E¹ ; Mostafaei S² ; Aslani S¹ ; Gharibdoost F¹ ; Xavier RM³ ; Salim PH³ ; Kavosi H¹ ; Farhadi E^{1, 4} ; Mahmoudi M^{1, 4}

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1. Rheumatology Research Center, Tehran University of Medical Sciences, Shariati Hospital, Kargar Ave, Tehran, Iran
2. Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
3. Universidade Federal do Rio Grande do Sul, Servico de Reumatologia, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
4. Inflammation Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Advances in rheumatology (London# England) Published:2020

Abstract

BACKGROUND: The results of investigations on the association between killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and the risk of systemic sclerosis (SSc) are inconsistent. To comprehensively evaluate the influence of KIR polymorphisms on the risk of SSc, this meta-analysis was performed. METHODS: A systematic literature search was performed in electronic databases including Scopus and PubMed/MEDLINE to find all available studies involving KIR gene family polymorphisms and SSc risk prior to July 2019. Pooled odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were measured to detect associations between KIR gene family polymorphisms and SSc risk. RESULTS: Five articles, comprising 571 patients and 796 healthy participants, evaluating the KIR gene family polymorphisms were included in the final meta-analysis according to the inclusion and exclusion criteria, and 16 KIR genes were assessed. None of the KIR genes were significantly associated with the risk of SSc. CONCLUSIONS: The current meta-analysis provides evidence that KIR genes might not be potential risk factors for SSc risk.

Style	Citing Format
MLA	Karimizadeh E, et al.. "Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis." Advances in rheumatology (London# England), vol. 60, no. 1, 2020, pp. 8-.
APA	Karimizadeh E, Mostafaei S, Aslani S, Gharibdoost F, Xavier RM, Salim PH, Kavosi H, Farhadi E, Mahmoudi M (2020). Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis. Advances in rheumatology (London# England), 60(1), 8-.
Chicago	Karimizadeh E, Mostafaei S, Aslani S, Gharibdoost F, Xavier RM, Salim PH, Kavosi H, Farhadi E, Mahmoudi M. "Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis." Advances in rheumatology (London# England) 60, no. 1 (2020): 8-.
Harvard	Karimizadeh E et al. (2020) 'Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis', Advances in rheumatology (London# England), 60(1), pp. 8-.
Vancouver	Karimizadeh E, Mostafaei S, Aslani S, Gharibdoost F, Xavier RM, Salim PH, et al.. Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis. Advances in rheumatology (London# England). 2020;60(1):8-.
BibTex	@article{ author = {Karimizadeh E and Mostafaei S and Aslani S and Gharibdoost F and Xavier RM and Salim PH and Kavosi H and Farhadi E and Mahmoudi M}, title = {Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis}, journal = {Advances in rheumatology (London# England)}, volume = {60}, number = {1}, pages = {8-}, year = {2020} }
RIS	TY - JOUR AU - Karimizadeh E AU - Mostafaei S AU - Aslani S AU - Gharibdoost F AU - Xavier RM AU - Salim PH AU - Kavosi H AU - Farhadi E AU - Mahmoudi M TI - Evaluation of the Association Between Kir Polymorphisms and Systemic Sclerosis: A Meta-Analysis JO - Advances in rheumatology (London# England) VL - 60 IS - 1 SP - 8 EP - PY - 2020 ER -

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