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Psychometric Properties of the Scale for Non-Adherence to Antiretroviral Medication (Name) Among Hiv-Infected Patients Publisher



Hosseini Z1 ; Eftkhar H2 ; Aghamolaei T1 ; Ebadi A3 ; Nedjat S4 ; Abbasian L5 ; Parast MH6
Authors
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Authors Affiliations
  1. 1. Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  2. 2. Department of Health Education and Promotion, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Behavioral Sciences Research Center (BSRC), Life Style Institute, Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran
  4. 4. Department of Epidemiology and Biostatistics, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Iranian Research Center of HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. School of Nursing and Allied Medical Sciences, Maragheh Faculty of Medical Sciences, Maragheh, Iran

Source: Archives of Public Health Published:2019


Abstract

Background: Adherence to HIV medication is necessary for long-term HIV disease management. The objective of this study was to develop and examine the psychometric properties of a scale for measuring the barriers of antiretroviral medication adherence among Iranian Patients. Method: This was a sequential, exploratory mixed methods investigation composed of two phases. In the qualitative phase, item pool generation and questionnaire designing was carried out through in-depth individual interviews and group discussions; in the quantitative phase, psychometric properties of the questionnaire were assessed. In both phases, the participants were people who were living with HIV/AIDS and were taking antiretroviral medications. Results: In the first phase, an item pool containing 181 statements related to barriers of adherence to antiretroviral medication was generated. In the second phase, item reduction was applied, and a questionnaire containing 30 items was developed. The psychometric properties of the questionnaire were assessed, which indicated good validity and reliability of the instrument. In exploratory factor analysis, the items were loaded on six factors that altogether explain for 61.98 of the variance. The Cronbach's alpha and the intra class correlation coefficient of the questionnaire was 0.91 and 0.80, respectively. Conclusion: This study provided a reliable and valid instrument to identify the barriers of adherence to antiretroviral medication in patients with HIV/AIDS. Identify these barriers and design of interventions to eliminate or reduce of barriers can be an effective means of enhancing adherence to antiretroviral medication among these patients. © 2019 The Author(s).