Transitional Meningioma After Fetal Liver-Derived Cell Suspension Allotransplant: A Case Report Publisher Pubmed



Nasliesfahani E^{1, 2} ; Ghadami M² ; Amini P¹ ; Amiri S¹ ; Ghodsi M¹ ; Rambod C¹ ; Tootee A² ; Larijani B² Show Affiliations
Source: Experimental and Clinical Transplantation Published:2017

Abstract

Diabetes mellitus is a disease with no definite cure. In recent years, stem cell transplant has led to treatment of various diseases including diabetes. We sought to report a type 1 diabetic patient with a brain mass, diagnosed as transitional meningioma, after a fetal hematopoietic stem cell transplant. A 57-year-old woman with type 1 diabetes who previously had undergone a fetal hematopoietic stem cell transplant, attended the clinic with a history of progressive bifrontal headaches accompanied by nausea, vomiting, and visual disturbances over the previous 8 months. Investigations revealed a 2-cm mass in the right temporal region. The patient underwent a craniotomy, and the lesion was removed and sent for pathological and genetic investigations. The results indicated transitional meningioma with the origin of transplanted fetal hematopoietic stem cells. To our knowledge, this is the first report of transitional meningioma as a result of stem cell transplant. Despite all unanswered questions about the safety of stem cell transplant, this novel therapy provides hope for patients with type 1 diabetes. © Baskent University 2017 Printed in Turkey. All Rights Reserved.