Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Dietary Magnesium Intake Is Inversely Associated With Ulcerative Colitis: A Case–Control Study Publisher



Sadeghi O1 ; Khademi Z2 ; Saneei P3, 4 ; Hassanzadehkeshteli A5, 6 ; Daghaghzadeh H6 ; Tavakkoli H6 ; Adibi P6 ; Esmaillzadeh A2, 4, 7
Authors
Show Affiliations
Authors Affiliations
  1. 1. Nutrition and Food Security Research Center, Department of Community Nutrition, Student Research Committee, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Medicine, University of Alberta, Edmonton, Canada
  6. 6. Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular–Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Crohn's and Colitis 360 Published:2024


Abstract

Background: Ulcerative colitis (UC) causes long-lasting inflammation and ulcers in the gut. Limited observational data are available linking dietary magnesium intake and UC. In the present study, we aimed to investigate the association between dietary magnesium intake and UC in adults. Methods: The current population-based case–control study was performed on 109 UC patients and 218 age (±2 years) and sex-matched controls. The diagnosis of UC was made according to the standard criteria by a gastroenterology specialist. Dietary intakes were assessed using a validated self-administrated 106-item dish-based Food Frequency Questionnaire (FFQ). We also used a pretested questionnaire to collect data on potential confounders. Results: Individuals in the top tertile of magnesium intake were less likely to have UC compared with those in the bottom tertile. A significant inverse relationship was found between dietary magnesium intake and UC (odds ratio [OR]: 0.32, 95% confidence interval [CI]: 0.18–0.59) in the crude model. This relationship was also observed when we took several potential confounding into account (OR: 0.30, 95% CI: 0.14–0.68). Conclusions: Adherence to a magnesium-rich diet may have a role in preventing UC. However, further studies are needed to confirm our findings. © The Author(s) 2024.
Related Docs
View other Related Docs
1. Fruit and Vegetable Consumption in Relation to Primary Headaches: The Mephasous Study, Eating and Weight Disorders (2021)
2. Breakfast Consumption Is Inversely Associated With Primary Headaches in University Students: The Mephasous Study, Complementary Therapies in Medicine (2021)
3. The Relationship Between the World Index for Sustainability and Health (Wish) Score and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2024)
4. Effects of Soy Milk Consumption on Gut Microbiota, Inflammatory Markers, and Disease Severity in Patients With Ulcerative Colitis: A Study Protocol for a Randomized Clinical Trial, Trials (2020)
5. Total, Dietary, and Supplemental Magnesium Intakes and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies, Advances in Nutrition (2021)
6. Dairy Consumption in Relation to Primary Headaches Among a Large Population of University Students: The Mephasous Study, Complementary Therapies in Medicine (2020)
7. Association Between Magnesium Concentrations and Prediabetes: A Systematic Review and Meta-Analysis, Scientific Reports (2021)
8. Association of Plant-Based Dietary Patterns With Psychological Profile and Obesity in Iranian Women, Clinical Nutrition (2020)
Experts (# of related papers)
View all Related Experts
Ahmad Esmaillzadeh (7)
Leila Azadbakht (5)
Other Related Docs
9. Associations Between Dietary Intake of B-Vitamins and Psychological Disorders Among Iranian Women: A Cross-Sectional Study, Public Health Nutrition (2021)
10. Dietary Methyl Donor Micronutrients Intake in Relation to Psychological Disorders in Adults, British Journal of Nutrition (2022)
11. The Role of Magnesium in Different Inflammatory Diseases, Inflammopharmacology (2019)
12. Legume and Nuts Consumption in Relation to Odds of Breast Cancer: A Case-Control Study, Nutrition and Cancer (2021)
13. Consumption of Dairy Products and Odds of Ulcerative Colitis: An Iranian Case–Control Study, Food Science and Nutrition (2024)
14. Breakfast Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies, Nutritional Neuroscience (2022)
15. Adherence to Mediterranean Dietary Pattern Is Inversely Associated With Depression, Anxiety and Psychological Distress, Nutritional Neuroscience (2021)
16. A Case–Control Study on the Association Between Adherence to a Mediterranean-Style Diet and Breast Cancer, Frontiers in Nutrition (2023)