A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage

A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage Publisher Pubmed

Shafie M¹ ; Shahmohamadi E¹ ; Hadizadeh A¹ ; Hasanzadeh A¹ ; Gholampour G¹ ; Parsa S²

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1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Cancer Reports Published:2023

Abstract

Background: Disseminated intravascular coagulation (DIC) has been reported in various solid malignancies and is a common coagulation-related complication in prostate cancer. However, DIC has been rarely reported as the initial presentation of prostate cancer. Herein, we reported a patient referring with subdural hemorrhage (SDH) and DIC with an unexplained cause who was later diagnosed with prostate cancer. Case Presentation: We presented a 68-year-old man who was referred to the hospital with a gradual deterioration of consciousness, dyspnea, and edema in the genitalia and lower limbs. His primary laboratory tests showed elevated prothrombin time (PT) and partial thromboplastin time (PTT) and a decreased fibrinogen level of 47 mg/dL [200–400 mg/dL]. The DIC score was 7, which was suggestive of DIC. Moreover, cranial imaging showed SDH. Further work-up revealed elevated prostate-specific antigen and prostate enlargement with a mass effect on the bladder with a bone lesion, which was suggestive of metastatic prostate cancer. Conclusion: This report highlights DIC as a possible initial presentation of an underlying malignancy, as well as the importance of treatment of underlying disease in the management of DIC. A comprehensive and systematic work-up is essential for early diagnosis in patients with DIC to avoid further complications and mortality. © 2023 The Authors. Cancer Reports published by Wiley Periodicals LLC.

Style	Citing Format
MLA	Shafie M, et al.. "A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage." Cancer Reports, vol. 6, no. 9, 2023, pp. -.
APA	Shafie M, Shahmohamadi E, Hadizadeh A, Hasanzadeh A, Gholampour G, Parsa S (2023). A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage. Cancer Reports, 6(9), -.
Chicago	Shafie M, Shahmohamadi E, Hadizadeh A, Hasanzadeh A, Gholampour G, Parsa S. "A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage." Cancer Reports 6, no. 9 (2023): -.
Harvard	Shafie M et al. (2023) 'A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage', Cancer Reports, 6(9), pp. -.
Vancouver	Shafie M, Shahmohamadi E, Hadizadeh A, Hasanzadeh A, Gholampour G, Parsa S. A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage. Cancer Reports. 2023;6(9):-.
BibTex	@article{ author = {Shafie M and Shahmohamadi E and Hadizadeh A and Hasanzadeh A and Gholampour G and Parsa S}, title = {A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage}, journal = {Cancer Reports}, volume = {6}, number = {9}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Shafie M AU - Shahmohamadi E AU - Hadizadeh A AU - Hasanzadeh A AU - Gholampour G AU - Parsa S TI - A Rare Case of Prostate Cancer Initially Presented by Disseminated Intravascular Coagulation-Related Subdural Hemorrhage JO - Cancer Reports VL - 6 IS - 9 SP - EP - PY - 2023 ER -

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