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Novel 1,2,3,4-Tetrahydroquinazolinones Via Reaction of 2-Amino-N-Substituted Benzamides and Dimethyl Acetylenedicarboxylate Publisher



Nahavandian S1 ; Allameh S1 ; Saeedi M2, 3 ; Ansari S4 ; Mahdavi M4 ; Foroumadi A4 ; Shafiee A4
Authors

Source: Helvetica Chimica Acta Published:2015


Abstract

Reaction of 2-amino-N-substituted benzamides and dimethyl acetylenedicarboxylate (DMAD) in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in H2O at room temperature led to the formation of novel 1,2,3,4-tetrahydroquinazolinones. © 2015 Verlag Helvetica Chimica Acta AG, Zurich.
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