The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose

The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis Publisher

Jafari N¹ ; Shoaibinobarian N² ; Dehghani A³ ; Rad A⁴ ; Mirmohammadali SN⁵ ; Alaeian MJ⁶ ; Hamedi Y⁷ ; Zamani M⁸ ; Goudarzi MA⁹ ; Asbaghi O¹⁰

Show Affiliations

1. University of Applied Science and Technology - Allameh Tabarsi Center, Tehran, Iran
2. Department of Nutrition, School of Medical Sciences and Technologies, Islamic Azad University, Science and Research Branch, Tehran, Iran
3. Nutrition Research Center, Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
4. Nutrition Department, Faculty of Health and Nutrition, Lorestan University of Medical Sciences, Khoramabad, Iran
5. Department of Food, Nutrition, Dietetics and Health, Kansas State University, Manhattan, KS, United States
6. MD graduated from Shahid Beheshti University of Medical sciences, Tehran, Iran
7. Department of Physical Education, Central Tehran Branch, Islamic Azad University, Tehran, Iran
8. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
9. Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
10. Cancer Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran

Source: Food Science and Nutrition Published:2023

Abstract

Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aimed at conducting a systematic review and meta-analysis on the effect of purslane on glycemic profile and oxidative stress markers. A systematic search was performed in the Scopus, Web of science, PubMed and the Cochrane Library to find articles related to the effect of the purslane on Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) up to September 2022. Among the 611 initial studies that were identified from searching electronic databases, 16 Randomized Clinical Trials (RCTs) involving 1122 participants (557 cases and 565 controls) were included for data analysis. The results of random-effects modeling demonstrated that purslane consumption significantly reduced FBS (p <.001), MDA (p <.001) and increased TAC (p <.001). However, purslane consumption did not affect HbA1c (p <.109), fasting insulin (p =.298) and HOMA-IR (p =.382). Meta-analyses were performed using both the random- and fixed-effects model where appropriate, and I2 index was used to evaluate the heterogeneity. This meta-analysis study suggests that purslane has beneficial effects on oxidative stress markers and glycemic parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of its benefits and negligible adverse effects. © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.

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Style	Citing Format
MLA	Jafari N, et al.. "The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis." Food Science and Nutrition, vol. 11, no. 6, 2023, pp. 2530-2546.
APA	Jafari N, Shoaibinobarian N, Dehghani A, Rad A, Mirmohammadali SN, Alaeian MJ, Hamedi Y, Zamani M, Goudarzi MA, Asbaghi O (2023). The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis. Food Science and Nutrition, 11(6), 2530-2546.
Chicago	Jafari N, Shoaibinobarian N, Dehghani A, Rad A, Mirmohammadali SN, Alaeian MJ, Hamedi Y, Zamani M, Goudarzi MA, Asbaghi O. "The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis." Food Science and Nutrition 11, no. 6 (2023): 2530-2546.
Harvard	Jafari N et al. (2023) 'The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis', Food Science and Nutrition, 11(6), pp. 2530-2546.
Vancouver	Jafari N, Shoaibinobarian N, Dehghani A, Rad A, Mirmohammadali SN, Alaeian MJ, et al.. The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis. Food Science and Nutrition. 2023;11(6):2530-2546.
BibTex	@article{ author = {Jafari N and Shoaibinobarian N and Dehghani A and Rad A and Mirmohammadali SN and Alaeian MJ and Hamedi Y and Zamani M and Goudarzi MA and Asbaghi O}, title = {The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis}, journal = {Food Science and Nutrition}, volume = {11}, number = {6}, pages = {2530-2546}, year = {2023} }
RIS	TY - JOUR AU - Jafari N AU - Shoaibinobarian N AU - Dehghani A AU - Rad A AU - Mirmohammadali SN AU - Alaeian MJ AU - Hamedi Y AU - Zamani M AU - Goudarzi MA AU - Asbaghi O TI - The Effects of Purslane Consumption on Glycemic Control and Oxidative Stress: A Systematic Review and Dose–Response Meta-Analysis JO - Food Science and Nutrition VL - 11 IS - 6 SP - 2530 EP - 2546 PY - 2023 ER -

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