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The Relationship Between Serum Level of Vitamin D3 and Osseointegration Around the Dental Implant Publisher Pubmed



Pourshahidi S1 ; Yousefain M1
Authors
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Authors Affiliations
  1. 1. Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Oral Implantology Published:2021


Abstract

At present, dental implants are used more than before, and their high success rate is attributed to sufficient osseointegration, which depends on prosthetic-, implant-, and patient-related factors. The quality and quantity of bone and the host response are the main patient-related factors. Vitamin D3 affects bone metabolism by stimulating both osteoclasts and osteoblasts. This study aimed to review the human studies on the efficacy of vitamin D3 for dental implant osseointegration. Search of the literature yielded only 4 studies on human models, of which 2 showed the optimal efficacy of vitamin D3 for dental implant osseointegration, whereas the remaining 2 did not report any positive effect. However, this finding may be related to the small sample size of the vitamin D3-deficient group, which can compromise statistical analyses. In conclusion, vitamin D3 seems to be effective for dental implant osseointegration, although further research is required on human models. © 2021 Allen Press Inc.. All rights reserved.