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Hydrocephalus As the Sole Presentation of Primary Diffuse Large B-Cell Lymphoma of the Brain: Report of a Case and Review of Literature Publisher



Boshrabadi A1 ; Naiem A1 ; Ghazi Mirsaeid S1 ; Yarandi K1 ; Amirjamshidi A1
Authors
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Authors Affiliations
  1. 1. Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Surgical Neurology International Published:2017


Abstract

Background: The most common lymphoid malignancy in adults is diffuse large B-cell lymphoma (DLBCL). The median age of occurrence of DLBCL is between 6th and 7th decade of life, although some other types of aggressive non-Hodgkin's lymphomas (NHL) are present in younger age. Primary central nervous system lymphoma (PCNSL) is an uncommon type of extranodal NHL, which is either more prevalent or is diagnosed more often than before. Case Description: A 22-year-old man with ventriculoperitoneal shunt (VPS) performed at another center was referred with manifestations of shunt malfunction, unusual behavior, dysphasia, and hallucination. The shunt malfunction was handled appropriately several times and exploration of the enhancing cystic temporal lesion confirmed the diagnosis of DLBCL. Conclusion: In this communication, we intend to highlight the issue that hydrocephalus refractory to several interventions can be the sole manifestation of PCNSL and needs special clinical considerations. © 2017 Surgical Neurology International | Published by Wolters Kluwer - Medknow.