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Immunotoxicity of Mercury: Pathological and Toxicological Effects Publisher Pubmed



Maqbool F1, 2 ; Niaz K1, 2 ; Hassan FI1, 2 ; Khan F1, 2 ; Abdollahi M1, 2, 3, 4
Authors
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Authors Affiliations
  1. 1. International Campus, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Toxicology and Diseases Group, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews Published:2017


Abstract

Mercury (Hg) is toxic and hazardous metal that causes natural disasters in the earth's crust. Exposure to Hg occurs via various routes; like oral (fish), inhalation, dental amalgams, and skin from cosmetics. In this review, we have discussed the sources of Hg and its potential for causing toxicity in humans. In addition, we also review its bio-chemical cycling in the environment; its systemic, immunotoxic, genotoxic/carcinogenic, and teratogenic health effects; and the dietary influences; as well as the important considerations in risk assessment and management of Hg poisoning have been discussed in detail. Many harmful outcomes have been reported, which will provide more awareness. © 2017 Taylor & Francis Group, LLC.