Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers

Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers Publisher

Akhyani M¹ ; Hatami P¹ ; Yadegarfar Z¹ ; Ghanadan A^{2, 3}

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1. Autoimmune Bullous Diseases Research Centre, Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Iran
2. Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Iran
3. Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Dermatological Case Reports Published:2015

Abstract

Background: Colloid milium is a rare cutaneous deposition disorder characterized by translucent papules developing on sun-exposed regions such as the face, neck and dorsal aspects of the hands and back. Exogenous ochronosis is caused by the accumulation of homogentisic acid resulting from long-term application of certain topical agents. Histology is characterized by yellow-brown pigment deposits in the papillary dermis. Prolonged use of hydroquinone may result in the development of the pigmented form of colloid milium, sometimes in association with ochronosis. Case report: A 53-year-old man presented with a 3-year history of multiple slow spreading pigmented papules on the dorsa of his hands, nose and ears. The patient had a long history of exposure to sun and fertilizers with no history of using hydroquinone bleaching creams. A later biopsy revealed the diagnosis of pigmented colloid milium associated with exogenous ochronosis. Conclusion: UV light damage and long contact with fertilizers may have a role in the development of pigmented colloid milium associated with exogenous ochronosis. © 2015, Specjalisci Dermatolodzy. All rights reserved.

Style	Citing Format
MLA	Akhyani M, et al.. "Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers." Journal of Dermatological Case Reports, vol. 9, no. 2, 2015, pp. 42-45.
APA	Akhyani M, Hatami P, Yadegarfar Z, Ghanadan A (2015). Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers. Journal of Dermatological Case Reports, 9(2), 42-45.
Chicago	Akhyani M, Hatami P, Yadegarfar Z, Ghanadan A. "Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers." Journal of Dermatological Case Reports 9, no. 2 (2015): 42-45.
Harvard	Akhyani M et al. (2015) 'Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers', Journal of Dermatological Case Reports, 9(2), pp. 42-45.
Vancouver	Akhyani M, Hatami P, Yadegarfar Z, Ghanadan A. Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers. Journal of Dermatological Case Reports. 2015;9(2):42-45.
BibTex	@article{ author = {Akhyani M and Hatami P and Yadegarfar Z and Ghanadan A}, title = {Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers}, journal = {Journal of Dermatological Case Reports}, volume = {9}, number = {2}, pages = {42-45}, year = {2015} }
RIS	TY - JOUR AU - Akhyani M AU - Hatami P AU - Yadegarfar Z AU - Ghanadan A TI - Pigmented Colloid Milium Associated With Exogenous Ochronosis in a Farmer With Long-Term Exposure to Fertilizers JO - Journal of Dermatological Case Reports VL - 9 IS - 2 SP - 42 EP - 45 PY - 2015 ER -

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