The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients

The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients Publisher Pubmed

Moradbeigi M¹ ; Seyedalinaghi S² ; Sajadipour M² ; Dadras O³ ; Shojaei E² ; Ahmadi P⁴ ; Bayanolhagh S² ; Baesi K⁵ ; Rasoolinejad M²

Show Affiliations

1. Department of Clinical Biochemistry, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Global Health and Socioepidemiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
4. Chemistry Faculty, Khajenasir Toosi University of Technology, Tehran, Iran
5. Hepatitis and AIDS Department, Pasteur Institute of Iran, Tehran, Iran

Source: Infectious Disorders - Drug Targets Published:2020

Abstract

Objective: This study aimed to simultaneously measure and assess the correlation between the available HIV infection parameters including HIV antibody, p24 Antigen, CD4 cell count, and viral load at the different stages of HIV disease among HIV-positive individuals in Iran. Materials and Methods: Fifty HIV-positive individuals were classified into three stages (1, 2, and 3) according to the HIV disease stages classification, available in Control of Disease and Prevention (CDC) guideline. 10 ml of the venous blood sample was collected to run the tests for HIV antibody and p24 Ag levels, CD4 cell counts, and viral load. Pearson’s correlation test was em-ployed to calculate the coefficients for the in-between correlation of different HIV parameters in each stage. Results: Of 50 participants, 17 (34%), 25 (50%), and 8 (16%) patients belonged to stages 1, 2, and 3, respectively. Sexual relationship was the main route of HIV transmission among the patients (36%); however, injecting drug use (20%) was also reported frequently. There was no significant correlation between the parameters of HIV disease in different stages in the present study. Conclusion: The findings showed no correlation between HIV parameters in the present study. Considering the fact that the association of HIV antibodies with HIV disease progression in infected individuals is independent of HIV-1 RNA levels, combined measurement of HIV-1 RNA and CD4 cell counts should be routinely carried out in HIV infected patients follow up. © 2020 Bentham Science Publishers.

Style	Citing Format
MLA	Moradbeigi M, et al.. "The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients." Infectious Disorders - Drug Targets, vol. 20, no. 5, 2020, pp. 752-757.
APA	Moradbeigi M, Seyedalinaghi S, Sajadipour M, Dadras O, Shojaei E, Ahmadi P, Bayanolhagh S, Baesi K, Rasoolinejad M (2020). The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients. Infectious Disorders - Drug Targets, 20(5), 752-757.
Chicago	Moradbeigi M, Seyedalinaghi S, Sajadipour M, Dadras O, Shojaei E, Ahmadi P, Bayanolhagh S, Baesi K, Rasoolinejad M. "The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients." Infectious Disorders - Drug Targets 20, no. 5 (2020): 752-757.
Harvard	Moradbeigi M et al. (2020) 'The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients', Infectious Disorders - Drug Targets, 20(5), pp. 752-757.
Vancouver	Moradbeigi M, Seyedalinaghi S, Sajadipour M, Dadras O, Shojaei E, Ahmadi P, et al.. The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients. Infectious Disorders - Drug Targets. 2020;20(5):752-757.
BibTex	@article{ author = {Moradbeigi M and Seyedalinaghi S and Sajadipour M and Dadras O and Shojaei E and Ahmadi P and Bayanolhagh S and Baesi K and Rasoolinejad M}, title = {The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients}, journal = {Infectious Disorders - Drug Targets}, volume = {20}, number = {5}, pages = {752-757}, year = {2020} }
RIS	TY - JOUR AU - Moradbeigi M AU - Seyedalinaghi S AU - Sajadipour M AU - Dadras O AU - Shojaei E AU - Ahmadi P AU - Bayanolhagh S AU - Baesi K AU - Rasoolinejad M TI - The Relationship Between Hiv Antibody Titer, Hiv Viral Load, Hiv P24 Antigen, and Cd4 T-Cell Count Among Iranian Hiv-Positive Patients JO - Infectious Disorders - Drug Targets VL - 20 IS - 5 SP - 752 EP - 757 PY - 2020 ER -

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