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Sofosbuvir As a Potential Option for the Treatment of Covid-19 Publisher Pubmed



Nourian A1 ; Khalili H1
Authors
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Authors Affiliations
  1. 1. Department of Pharmacotherapy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Biomedica Published:2020


Abstract

Summary. Sofosbuvir may be a potential option in the treatment of COVID-19 based on the similarity between the replication mechanisms of the HCV and the coronavirus. According the limited experimental evidences, it is hypothesized that sofosbuvir might be a potential option to improve care of patients with COVID-19 especially at the start of the disease and before invasion of the virus into the lung parenchymal cells. Efficacy and safety of sofosbuvir in treatment of COVID-19 may be considered in future clinical studies. (www.actabiomedica.it). © Mattioli 1885.