Ameloblastic Carcinoma With Calcification: A Rare Case Report in the Mandible and Literature Review Publisher

Summary: Did you know ameloblastic carcinoma (AC) can be mistaken for benign tumors? Research suggests AC poses unique challenges in diagnosis, needing aggressive treatment. What else should clinicians beware of? #CancerResearch #OralPathology

Khoozestani NK¹ ; Mosavat F² ; Shirkhoda M³ ; Azar R²
Source: Case Reports in Dentistry Published:2020

Abstract

Ameloblastic carcinoma (AC) is a scarce malignant tumor which is more prevalent in the mandible than the maxilla. It occurs in a wide range of age groups, and there is a sex predilection in males. AC shows specific microscopic features and requires more aggressive surgical treatment plans in comparison with conventional ameloblastoma. Radiographically, AC resembles ameloblastoma except that it rarely represents focal mineralized materials, seemingly reflecting dystrophic calcification. This characteristic is uncommon in typical ameloblastomas, and only few cases reported with such opacities and mineralized materials. Due to this rare radiographic and microscopic presentation, an accurate diagnosis could be challenging, and pathologists should consider a combination of benign and malignant odontogenic tumors occurring in jaws. © 2020 Neda Kardouni Khoozestani et al.