An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines

An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines Publisher Pubmed

Sayahi MH¹ ; Baghersaei S¹ ; Goli F² ; Moghimi S² ; Mahdavi M² ; Firoozpour L³ ; Shafiee A² ; Foroumadi A^{2, 3}

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1. Department of Chemistry, Payame Noor Universtiy (PNU), P.O. Box 19395-3697, Tehran, Iran
2. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Combinatorial Chemistry and High Throughput Screening Published:2016

Abstract

Herein, we describe a simple, four-step process for the preparation of 1,2,3-triazino[1,6-a]quinazolin-13-ones. This method involves ring-opening, quinazoline-forming condensation, reduction, diazotization accompanied by rapid intramolecular cyclization in the last step afforded the desired products with structurally complex heterocyclic core in excellent to high yields. © 2016 Bentham Science Publishers.

2. Synthesis and Antiacetylcholinesterase Activity Evaluation of New 2-Aryl Benzofuran Derivatives, Letters in Drug Design and Discovery (2016)

3. Synthesis of Novel Fused Quinazolinone Derivatives, Molecular Diversity (2016)

4. Three-Component One-Pot Synthesis of Dihydrochromeno[4,3-B]Pyrazolo[4,3-E]Pyridines, Heterocyclic Communications (2016)

5. Synthesis, Molecular Docking, and Cytotoxicity of Quinazolinone and Dihydroquinazolinone Derivatives As Cytotoxic Agents, BMC Chemistry (2022)

6. Isatoic Anhydride: A Fascinating and Basic Molecule for the Synthesis of Substituted Quinazolinones and Benzo Di/Triazepines, Current Organic Chemistry (2019)

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Mohammad Mahdavi (6)

Alireza Foroumadi (3)

Style	Citing Format
MLA	Sayahi MH, et al.. "An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines." Combinatorial Chemistry and High Throughput Screening, vol. 19, no. 3, 2016, pp. 189-192.
APA	Sayahi MH, Baghersaei S, Goli F, Moghimi S, Mahdavi M, Firoozpour L, Shafiee A, Foroumadi A (2016). An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines. Combinatorial Chemistry and High Throughput Screening, 19(3), 189-192.
Chicago	Sayahi MH, Baghersaei S, Goli F, Moghimi S, Mahdavi M, Firoozpour L, Shafiee A, Foroumadi A. "An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines." Combinatorial Chemistry and High Throughput Screening 19, no. 3 (2016): 189-192.
Harvard	Sayahi MH et al. (2016) 'An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines', Combinatorial Chemistry and High Throughput Screening, 19(3), pp. 189-192.
Vancouver	Sayahi MH, Baghersaei S, Goli F, Moghimi S, Mahdavi M, Firoozpour L, et al.. An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines. Combinatorial Chemistry and High Throughput Screening. 2016;19(3):189-192.
BibTex	@article{ author = {Sayahi MH and Baghersaei S and Goli F and Moghimi S and Mahdavi M and Firoozpour L and Shafiee A and Foroumadi A}, title = {An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines}, journal = {Combinatorial Chemistry and High Throughput Screening}, volume = {19}, number = {3}, pages = {189-192}, year = {2016} }
RIS	TY - JOUR AU - Sayahi MH AU - Baghersaei S AU - Goli F AU - Moghimi S AU - Mahdavi M AU - Firoozpour L AU - Shafiee A AU - Foroumadi A TI - An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines JO - Combinatorial Chemistry and High Throughput Screening VL - 19 IS - 3 SP - 189 EP - 192 PY - 2016 ER -

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