The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview

The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview Publisher

Masoudkabir F^{1, 2} ; Bayani R³ ; Mousavi Darzikolaee N^{4, 5} ; Abdshah A^{6, 7} ; Moshtaghian M⁸ ; Farhan F⁸ ; Aghili M⁸ ; Kazemian A^{5, 8} ; Nicosia L⁹ ; Cuccia F⁹ ; Rocha AV¹⁰ ; Jafari F⁸ ; Alongi F^{9, 11}

Show Affiliations

1. Cardiac Primary Prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Cardiac Electrophysiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Radiation Oncology, Hamadan University of Medical Sciences, Hamadan, Iran
4. Radiation Oncology Research Center (RORC), Tehran University of Medical Sciences, Tehran, Iran
5. Department of Radiation Oncology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
6. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
7. Division of Biostatistics, University of Miami Miller School of Medicine, Miami, FL, United States
8. Cancer Research Center, Cancer institute of Iran, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
9. Advanced Radiation Oncology Department, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar-Verona, Italy
10. Division of Medicine, Federal University of Goias, Goiania, Brazil
11. University of Brescia, Brescia, Italy

Source: Health Science Reports Published:2023

Abstract

Introduction: Cardiac arrhythmias, including ventricular tachycardia (VT), stand as a significant threat to health, often leading to mortality and sudden cardiac death. While conventional treatments for VT exhibit efficacy, cases of refractory VT pose challenges. Stereotactic Arrhythmia Radioablation (STAR) offers a novel approach, delivering precise high-dose radiation to well-defined targets with minimal collateral damage. This study explores the potential of STAR as an alternative therapy, especially for high-risk patients or those with refractory VT. Methods: This research reviews ongoing studies and preliminary investigations into the evaluation of the efficacy and safety of STAR. The method involves targeted radiation delivery, assessing reductions in VT recurrence and the early safety profile in refractory VT patients. However, given STAR's early stage and limited clinical evidence, cautious interpretation is advised. Results: Preliminary findings indicate a reduction in VT recurrence with STAR, suggesting promise as a therapeutic option. Early safety profiles are encouraging, but definitive statements on efficacy and safety require further investigation. Positive initial outcomes underscore the need for additional data and long-term studies. Conclusion: Stereotactic Arrhythmia Radioablation is recently emerging as a promising treatment for refractory VT. While early results are encouraging, careful interpretation is needed, due to STAR's early stages. Ongoing investigations are critical for a comprehensive understanding of its long-term efficacy and tolerability. This review provides fundamental insights into STAR's background, principles, pre-treatment procedures, clinical implications, and toxicity, setting the stage for future research in this evolving therapeutic field. © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.

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Safura Jokar (1)

Style	Citing Format
MLA	Masoudkabir F, et al.. "The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview." Health Science Reports, vol. 6, no. 12, 2023, pp. -.
APA	Masoudkabir F, Bayani R, Mousavi Darzikolaee N, Abdshah A, Moshtaghian M, Farhan F, Aghili M, Kazemian A, Nicosia L, Cuccia F, Rocha AV, Jafari F, Alongi F (2023). The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview. Health Science Reports, 6(12), -.
Chicago	Masoudkabir F, Bayani R, Mousavi Darzikolaee N, Abdshah A, Moshtaghian M, Farhan F, Aghili M, et al.. "The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview." Health Science Reports 6, no. 12 (2023): -.
Harvard	Masoudkabir F et al. (2023) 'The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview', Health Science Reports, 6(12), pp. -.
Vancouver	Masoudkabir F, Bayani R, Mousavi Darzikolaee N, Abdshah A, Moshtaghian M, Farhan F, et al.. The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview. Health Science Reports. 2023;6(12):-.
BibTex	@article{ author = {Masoudkabir F and Bayani R and Mousavi Darzikolaee N and Abdshah A and Moshtaghian M and Farhan F and Aghili M and Kazemian A and Nicosia L and Cuccia F and Rocha AV and Jafari F and Alongi F}, title = {The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview}, journal = {Health Science Reports}, volume = {6}, number = {12}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Masoudkabir F AU - Bayani R AU - Mousavi Darzikolaee N AU - Abdshah A AU - Moshtaghian M AU - Farhan F AU - Aghili M AU - Kazemian A AU - Nicosia L AU - Cuccia F AU - Rocha AV AU - Jafari F AU - Alongi F TI - The State-Of-The-Art Technic of Stereotactic Radioablation for the Treatment of Cardiac Arrhythmias: An Overview JO - Health Science Reports VL - 6 IS - 12 SP - EP - PY - 2023 ER -

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