Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones

Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones Publisher

Kianmehr E¹ ; Falahat MR¹ ; Tanbakouchian A¹ ; Mahdavi M²

Show Affiliations

1. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: European Journal of Organic Chemistry Published:2020

Abstract

Copper mediated cyanatation of N-(quinoline-8-yl)benzamides with cyanate salts and subsequent intramolecular cyclization of the resulting product was accomplished. Different derivatives of quinazoline-2,4(1H,3H)-dione bearing quinoline-8-yl directing group were readily prepared in moderate to high yields by this methodology from easily accessible starting materials through cascade directed C–H bond functionalization/annulation reactions. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Style	Citing Format
MLA	Kianmehr E, et al.. "Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones." European Journal of Organic Chemistry, vol. 2020, no. 6, 2020, pp. 708-713.
APA	Kianmehr E, Falahat MR, Tanbakouchian A, Mahdavi M (2020). Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones. European Journal of Organic Chemistry, 2020(6), 708-713.
Chicago	Kianmehr E, Falahat MR, Tanbakouchian A, Mahdavi M. "Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones." European Journal of Organic Chemistry 2020, no. 6 (2020): 708-713.
Harvard	Kianmehr E et al. (2020) 'Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones', European Journal of Organic Chemistry, 2020(6), pp. 708-713.
Vancouver	Kianmehr E, Falahat MR, Tanbakouchian A, Mahdavi M. Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones. European Journal of Organic Chemistry. 2020;2020(6):708-713.
BibTex	@article{ author = {Kianmehr E and Falahat MR and Tanbakouchian A and Mahdavi M}, title = {Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones}, journal = {European Journal of Organic Chemistry}, volume = {2020}, number = {6}, pages = {708-713}, year = {2020} }
RIS	TY - JOUR AU - Kianmehr E AU - Falahat MR AU - Tanbakouchian A AU - Mahdavi M TI - Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones JO - European Journal of Organic Chemistry VL - 2020 IS - 6 SP - 708 EP - 713 PY - 2020 ER -

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