Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study

Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study Publisher Pubmed

Sharbaf FR¹ ; Shirazi M² ; Haghiri M² ; Shariat M² ; Niroomanesh S¹ ; Ghaemi M³ ; Khalilabadi SM⁴

Show Affiliations

1. Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Obstetrics and Gynecology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

Source: Archives of Iranian Medicine Published:2022

Abstract

Background: Selective reduction of the fetus is one of the therapeutic methods in complicated monochorionic twins. The present study aimed to investigate the success rate and perinatal outcomes of selective reduction using radiofrequency ablation (RFA) in monochorionic multiple pregnancies with a hydropic fetus. Methods: This prospective interventional single-arm study was conducted in a referral hospital from 2017 to 2019. Totally, 27 complicated monochorionic twin and triplet pregnancies underwent RFA to occlude the umbilical vein of the hydropic fetus. The participants were followed until 2 months post-delivery. Procedure success rate, survival rate, gestational age at delivery, and neonatal outcome were evaluated. Results: The umbilical cord in 26 (96.2%) cases was successfully occluded by RFA with no maternal complications. Live birth was within 75%. The mean ± SD age at delivery was 34.4 ± 3.83 weeks. The gestational age at delivery in TTTS (twin-to-twin transfusion syndrome)-induced hydrops was significantly lower than the non-TTTS hydrops group (P= 0.003). Four cases experienced preterm premature rupture of the membranes (PPROM) before 34 weeks. Of all viable neonates, 8 cases were admitted to the neonatal intensive care unit (NICU). In 2 months follow-up post-delivery, all neonates had normal findings without any adverse outcomes. Conclusion: Selective reduction by RFA in complicated monochorionic pregnancies with a hydropic fetus may be a safe method with a high success rate and 100% neonatal survival. This method may be optimal for feticide in non-TTTS hydropic twins. © 2022 Academy of Medical Sciences of I.R. Iran. All rights reserved.

Related Docs

View other Related Docs

1. Selective Reduction in Complicated Monochorionic Pregnancies: A Systematic Review and Meta-Analysis of Different Techniques, American Journal of Obstetrics and Gynecology (2022)

2. Radiofrequency Ablation for Selective Fetal Reduction in Complicated Monochorionic Twins; Comparing the Outcomes According to the Indications, BMC Pregnancy and Childbirth (2021)

3. Fetal Outcomes and Prognostic Factors After Radiofrequency Ablation for the Selective Reduction in Complicated Monochorionic Multiple Pregnancies, Academic Radiology (2023)

4. Comparison of Prenatal and Neonatal Outcomes of Selective Fetal Growth Restriction in Monochorionic Twin Pregnancies With or Without Twin-To-Twin Transfusion Syndrome After Radiofrequency Ablation, Iranian Journal of Medical Sciences (2022)

5. Early Detection of Ischemic Brain Injuries by Diffusion-Weighted Imaging After Radiofrequency Ablation for Fetal Reduction in Monochorionic Pregnancies, Journal of Clinical Ultrasound (2022)

6. Radiofrequency Ablation of Umbilical Cord for Reduction of Twin Reversed Arterial Perfusion Sequence: A Case Series and a Literature Review, Iranian Journal of Neonatology (2022)

7. Does Progesterone Prevent Preterm Labor in Complicated Monochorionic Twin Pregnancies After Radiofrequency Ablation of One Fetus?, Journal of Iranian Medical Council (2023)

8. Conjoined Twins in a Monochorionic Triplet Pregnancy After in Vitro Fertilization: A Case Report, International Journal of Reproductive BioMedicine (2015)

Experts (# of related papers)

View all Related Experts

Mahboobeh Shirazi (9)

Fatemeh Rahimi Sharbaf (8)

Style	Citing Format
MLA	Sharbaf FR, et al.. "Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study." Archives of Iranian Medicine, vol. 25, no. 1, 2022, pp. 6-11.
APA	Sharbaf FR, Shirazi M, Haghiri M, Shariat M, Niroomanesh S, Ghaemi M, Khalilabadi SM (2022). Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study. Archives of Iranian Medicine, 25(1), 6-11.
Chicago	Sharbaf FR, Shirazi M, Haghiri M, Shariat M, Niroomanesh S, Ghaemi M, Khalilabadi SM. "Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study." Archives of Iranian Medicine 25, no. 1 (2022): 6-11.
Harvard	Sharbaf FR et al. (2022) 'Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study', Archives of Iranian Medicine, 25(1), pp. 6-11.
Vancouver	Sharbaf FR, Shirazi M, Haghiri M, Shariat M, Niroomanesh S, Ghaemi M, et al.. Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study. Archives of Iranian Medicine. 2022;25(1):6-11.
BibTex	@article{ author = {Sharbaf FR and Shirazi M and Haghiri M and Shariat M and Niroomanesh S and Ghaemi M and Khalilabadi SM}, title = {Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study}, journal = {Archives of Iranian Medicine}, volume = {25}, number = {1}, pages = {6-11}, year = {2022} }
RIS	TY - JOUR AU - Sharbaf FR AU - Shirazi M AU - Haghiri M AU - Shariat M AU - Niroomanesh S AU - Ghaemi M AU - Khalilabadi SM TI - Success Rate and Perinatal Outcomes of Selective Reduction by Radiofrequency Ablation in Monochorionic Multiple Pregnancies With a Hydropic Fetus; a Prospective Interventional Single-Arm Study JO - Archives of Iranian Medicine VL - 25 IS - 1 SP - 6 EP - 11 PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract