Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks

Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks Publisher

Saeedi M¹ ; Goli F¹ ; Mahdavi M¹ ; Asadipour A² ; Shafiee A¹ ; Foroumadi A^{1, 2}

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1. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medicinal Sciences, Tehran, Iran
2. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medicinal Sciences, Kerman, Iran

Source: Journal of Heterocyclic Chemistry Published:2015

Abstract

In this work, an efficient and versatile synthesis of novel thiazol-2-ylidene-amides from various carbonylthiourea derivatives is described. A sequential alkylation-cyclization reaction between thioureas and propargyl bromide in the presence of DABCO in refluxing ethanol afforded 4-methylthiazol-2(3H)-ylidene-amide derivatives in good yields. © 2014 HeteroCorporation.

Style	Citing Format
MLA	Saeedi M, et al.. "Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks." Journal of Heterocyclic Chemistry, vol. 52, no. 4, 2015, pp. 1150-1153.
APA	Saeedi M, Goli F, Mahdavi M, Asadipour A, Shafiee A, Foroumadi A (2015). Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks. Journal of Heterocyclic Chemistry, 52(4), 1150-1153.
Chicago	Saeedi M, Goli F, Mahdavi M, Asadipour A, Shafiee A, Foroumadi A. "Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks." Journal of Heterocyclic Chemistry 52, no. 4 (2015): 1150-1153.
Harvard	Saeedi M et al. (2015) 'Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks', Journal of Heterocyclic Chemistry, 52(4), pp. 1150-1153.
Vancouver	Saeedi M, Goli F, Mahdavi M, Asadipour A, Shafiee A, Foroumadi A. Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks. Journal of Heterocyclic Chemistry. 2015;52(4):1150-1153.
BibTex	@article{ author = {Saeedi M and Goli F and Mahdavi M and Asadipour A and Shafiee A and Foroumadi A}, title = {Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks}, journal = {Journal of Heterocyclic Chemistry}, volume = {52}, number = {4}, pages = {1150-1153}, year = {2015} }
RIS	TY - JOUR AU - Saeedi M AU - Goli F AU - Mahdavi M AU - Asadipour A AU - Shafiee A AU - Foroumadi A TI - Efficient Synthesis of Novel Thiazol-2-Ylidene-Amides Using Carbonylthiourea Building Blocks JO - Journal of Heterocyclic Chemistry VL - 52 IS - 4 SP - 1150 EP - 1153 PY - 2015 ER -

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