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The Effect of Photobiomodulation Therapy on Implant Stability: A Systematic Review and Meta-Analysis Publisher Pubmed



Arshad M1, 2 ; Mazidi Y3 ; Chiniforush N4 ; Shirvani A5 ; Bassir SH6
Authors
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Authors Affiliations
  1. 1. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Prosthodontics, School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy
  5. 5. Pediatric Gastroenterology, Hepatology, and Nutrition Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. Department of Endodontics and Periodontics, Herman Ostrow School of Dentistry of USC, Los Angeles, United States

Source: Photochemistry and Photobiology Published:2025


Abstract

This study was designed to determine the effect of photobiomodulation therapy on dental implant stability. A complete systematic search was performed in PUBMED/MEDLINE, COCHRANE library databases, EMBASE, SCOPUS, and Google Scholar databases on articles published until June 2024. All the RCTs and CCTs reported the solo impact of photobiomodulation on dental implant stability in humans were included. The means and standard deviation for implant stability and sample size were extracted for the meta-analysis. The statistical analysis was conducted using Stata 17 software, and random effect models were applied to assess the source of heterogeneity. The I2 statistic was used to estimate the significance of any discrepancies in the therapy result. After a full-text inspection, 17 articles were qualified for systematic review, and 14 were included in the meta-analysis. Statically significant differences in implant stability were observed between the laser and the control groups on weeks 2 in ISQ reporting groups (p = 0.01, CI 95%) and weeks 4 and 8 in PTV reporting groups (p < 0.001, CI 95%). Despite limitations, the study suggests that PBM therapy benefits patients with dental implants at different periods, particularly during the early phases of healing. © 2024 American Society for Photobiology.
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