Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Prospective Epidemiological Research Studies in Iran (Persian) Birth Cohort Protocol: Rationale, Design and Methodology Publisher



Sakhvidi MJZ1 ; Danaei N2 ; Dadvand P3, 4, 5 ; Mehrparvar AH6 ; Heidaribeni M7 ; Nouripour S2 ; Nikukar H6 ; Daniali SS7 ; Saffarieh E2 ; Noorishadkam M6 ; Amin MM7 ; Mirmohammadkhani M2 ; Lotfi MH6 ; Vaez A7, 8 Show All Authors
Authors
  1. Sakhvidi MJZ1
  2. Danaei N2
  3. Dadvand P3, 4, 5
  4. Mehrparvar AH6
  5. Heidaribeni M7
  6. Nouripour S2
  7. Nikukar H6
  8. Daniali SS7
  9. Saffarieh E2
  10. Noorishadkam M6
  11. Amin MM7
  12. Mirmohammadkhani M2
  13. Lotfi MH6
  14. Vaez A7, 8
  15. Mirmohammadi SJ6
  16. Zarean E7
  17. Mojibian M6
  18. Hashemipour M7
  19. Yaghini O7
  20. Rezai MS9
  21. Esmaeili A10
  22. Fahimzad A11
  23. Hakimi H10
  24. Navaeifar MR9
  25. Ebrahimi HO10
  26. Poustchi H12
  27. Malekzadeh R12
  28. Kelishadi R7
Show Affiliations
Authors Affiliations
  1. 1. University of Medical Sciences, Iran
  2. 2. Semnan University of Medical Sciences, Iran
  3. 3. ISGlobal, Barcelona, Spain
  4. 4. Universitat Pompeu Fabra (UPF), Spain
  5. 5. CIBER Epidemiologia y Salud Publica (CIBERESP), Spain
  6. 6. Shahid Sadoughi University of Medical Sciences, Iran
  7. 7. Isfahan University of Medical Sciences, Iran
  8. 8. University of Groningen, Netherlands
  9. 9. Mazandaran University of Medical Sciences, Iran
  10. 10. Rafsanjan University of Medical Sciences, Iran
  11. 11. Shahid Beheshti University of Medical Sciences, Iran
  12. 12. Tehran University of Medical Sciences, Iran

Source: Longitudinal and Life Course Studies Published:2021


Abstract

Background: Birth cohorts are essential for developing evidence-based policies and advancing knowledge on different aspects of the concept of developmental origins of health and diseases (DOHaD). The Prospective Epidemiological Research Studies in IrAN (PERSIAN) is a multicentre cohort in Iran. It is one of the pioneers of DOHaD research in the Middle East and North Africa (MENA) region. This profile provides a brief overview of this birth cohort, focusing on the objectives and design of the study. The main objective of this birth cohort is to evaluate the associations of socio-economic characteristics, lifestyle, diet, environmental exposures and epigenetic factors with outcomes of: pregnancy; mother and child mental and physical health and well-being; child neurodevelopment; and the establishment of chronic disease risk factors. Methods: The enrolment of PERSIAN Birth Cohort participants is currently ongoing in five Iranian cities (Isfahan, Yazd, Semnan, Sari and Rafsanjan). We plan to recruit 15, 000 mother-offspring pairs, and to follow them for at least ten years. Data collection consists of three consecutive phases: (1) periconception until birth; (2) infancy (0-2 years); and (3) childhood (3-11 years). We are collecting data on both ‘determinants of health’ and ‘health outcomes’. In addition to questionnaires and physical examination, various biological samples, including blood, urine, hair, nail, cord blood and breastmilk are being collected. Growth and neurodevelopment of children will be monitored. Appropriate data analysis schemes will be employed to assess the role of early life factors in health and disease that would facilitate international comparisons. © Authors 2021.
Related Docs
1. Tehran Environmental and Neurodevelopmental Disorders (Tend) Cohort Study: Phase I, Feasibility Assessment, Journal of Environmental Health Science and Engineering (2020)
Experts (# of related papers)
View all Related Experts
Gholamreza Hassanpour (1)
Mohsen Vigeh (1)