Plant Protein Substitution for Animal Protein and Its Association With Cardiovascular Risk Factors and Inflammatory Biomarkers in Elderly Men: A Substitution Analysis Publisher



Abbasi H¹ ; Fahimfar N^{2, 3} ; Nazarzadeh M^{4, 5} ; Azadbakht L^{1, 6}
Source: Nutrition and Healthy Aging Published:2024

Abstract

BACKGROUND: Substituting different types of protein intake may be associated with cardiovascular risk factors and inflammatory biomarkers. However, there are few studies conducted on elders and the findings are contradictory. OBJECTIVE: We decided to examine the association of substituting plant protein for animal protein with cardiovascular risk factors and inflammatory biomarkers among elderly men. METHOD: The current cross-sectional study included 357 elderly men chosen from health centres in southern Tehran, Iran. They provide written consent to be included in the study. We used a validated and reliable food frequency questionnaire (FFQ) to assess dietary intake. All biochemical factors like lipid profile, fasting blood sugar (FBS), high sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL6), tumor necrosis factor-(TNF) were measured. Waist circumference (WC) and blood pressure (BP) were also assessed. The substitution analysis by STATA was used to examine the aforementioned association. RESULTS: Substituting animal protein with plant protein had significant beneficial association with WC (OR: –4.28; 95% CI: –8.51, –0.62; Ptrend = 0.047) and LDL/HDL (OR: –0.26; 95% CI: –0.48, –0.05; Ptrend = 0.018). CONCLUSION: In elderly men, substituting animal protein with plant protein had favorable association with some of cardiovascular risk factors including WC and LDL/HDL but there was no significant association for inflammatory biomarkers. © 2024 – The authors. Published by IOS Press.